New research has found that some of the human X chromosome originates from Neanderthals and is found exclusively in people outside Africa.
Neanderthals, whose ancestors left Africa somewhere in the range of 400,000 to 800,000 years ago, evolved in what is now France, Spain, Germany and Russia, and are believed to have lived until about 30,000 years ago. Early modern humans left Africa about 80,000 to 50,000 years ago.
The question on everyone's mind has always been whether the physically stronger Neanderthals, who possessed the gene for language and may have played the flute, were a separate species or could have interbred with modern humans. The answer, says
an international team of researchers writing in Molecular Biology and Evolution, is yes, the two lived in close association.
Almost a decade ago, they identified a haplotype in the human X chromosome that seemed different and whose origins they questioned. When the Neanderthal genome was sequenced in 2010, they quickly compared 6000 chromosomes from all parts of the world to the Neanderthal haplotype. The Neanderthal sequence was present in peoples across all continents, except for sub-Saharan Africa, and including Australia.
"This confirms recent findings suggesting that the two populations interbred," says Dr. Damian Labuda of the Department of Pediatrics at the University of Montreal and the CHU Sainte-Justine Research Center. His team places the timing of such intimate contacts and/or family ties early on, probably at the crossroads of the Middle East. "In addition, because our methods were totally independent of Neanderthal material, we can also conclude that previous results were not influenced by contaminating artifacts."
"Dr. Labuda and his colleagues were the first to identify a genetic variation in non-Africans that was likely to have come from an archaic population. This was done entirely without the Neanderthal genome sequence, but in light of the Neanderthal sequence, it is now clear that they were absolutely right!" adds Dr. David Reich, a Harvard Medical School geneticist, one of the principal researchers in the Neanderthal genome project.
"There is little doubt that this haplotype is present because of mating with our ancestors and Neanderthals. This is a very nice result, and further analysis may help determine more details," says Dr. Nick Patterson, of the Broad Institute of MIT and Harvard University, a major researcher in human ancestry who was not involved in this study.
So, speculates Dr. Labuda, did these exchanges contribute to our success across the world? "Variability is very important for long-term survival of a species," says Dr. Labuda. "Every addition to the genome can be enriching."
An interesting match, indeed.
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Top Mass: CMS Again On Top!
- The Enemy Of Archaeology Is Not People, It's Salt
- Science Graduates Are Not Good At Math – But Why?
- Wind Turbine Or Tree? Bats Can't Tell
- Depression Surveys Linked To Unnecessary Antidepressant Prescriptions
- The Origin Of Neptune And Uranus
- Why Ice Sheets Will Keep Melting For Centuries To Come
- "John you are almost invariably a negative nelly when responding on various blogs. Surprise us sometime..."
- "Regarding Vlad III. Drăculea, the Romanians still regard him as something of a hero. ..."
- "I just can't enthuse about the top quark because its existence has been inferred. It's ephemeral..."
- "Eventually, by analyzing LHC Run 2 data and combining all inputs, we will nail down the top quark..."
- "I've long pictured a brain as a bunch of rail yards, and signals are trains.When you're learning..."