Technology

The dye business of the 19th century was a mature, fast-moving and international industry, according to an analysis of four purple dresses. The study found that a brand new purple dye went from first synthesis to commercial use in just a few years.

Before the 1800s, purple dye came at a premium, so it was usually restricted to royalty -- hence the connection between royals and purple. The 19th century saw the discovery of several synthetic purple dyes, making purple textiles more affordable and readily available. Understanding where these dyes came from and were used is therefore of historical interest.

Can you trust any Yelp review when some restaurants create fake online restaurants as portals to avoid their own bad reviews, or pay for good ones? 

And as organizations like the American Council on Science and Health quickly learned, when a cabal of anti-science groups, like SourceWatch, US Right To Know, Natural News, and Joe Mercola team up with Mother Jones to undermine your work, the public will rightfully only look skin deep and not realize the negative press is being manufactured.

Research efforts on the intestine have increased in recent years. Owing to its enormous surface area - comparable to that of a one-bedroom apartment - and the huge number of neurons it contains - comparable to that in the brain - the intestine is sometimes referred to as the abdominal brain. In addition to absorbing nutrients from the foods we eat, it influences our immune status and metabolism.

With the help of sensors, specialized cells in the intestinal wall determine which hormones, if any, should be released into the bloodstream. Overall, it acts as a highly sophisticated control center.

How an organoid grows from cells

Due to disease-related changes in their brain, pain patients often suffer from an impaired tactile ability in their hands. In a pilot study conducted by scientists at the Ruhr-University Bochum, high frequency repetitive stimulation was investigated as a therapeutic approach for these patients. The results of this study have now been published in the journal "Frontiers in Neurology". They show that passive stimulation of this kind is a promising new therapy option.


Passive stimulation: a proven therapy approach


CRISPR-Cas9 is a hybrid of protein and RNA, the cousin to DNA, that functions as an efficient search-and-snip system in bacteria. It arose as a way to recognize and kill viruses, but then was adopted in other cells, including humans, to facilitate genome editing. The Cas9 protein, obtained from the bacteria Streptococcus pyogenes, functions together with a "guide" RNA that targets a complementary 20-nucleotide stretch of DNA. Once the RNA identifies a sequence matching these nucleotides, Cas9 cuts the double-stranded DNA helix.

In an eight-hour operation, Dr. Daniel Borsuk, doctor at Hôpital Maisonneuve-Rosemont in Montreal, carried out a facial reconstruction using virtual surgery and 3D models, removing a vascularized piece of pelvic bone and reshaping it to adapt it to the rest of the face before transplanting it through the inside of the mouth.

With no scars left at all.

In the past, this type of procedure would have necessitated multiple interventions and left one or more scars.

Everyone seems to know what the revenue of movies are, the film "Jem" and the new biopic of Steve Jobs being pulled from theaters after disastrous receptions are well known, but less known is that the video game industry is bigger - and therefore the budgets for games are sometimes as big.

 With the world population expected to reach 9 billion by 2050, engineers and scientists are looking for ways to meet the increasing demand for food without also increasing the strain on natural resources, such as water and energy, an initiative known as the food-water-energy nexus.

How does our brain develop the ability to perform complex cognitive functions, such as those needed for language and reasoning? This is a question that certainly we are all asking ourselves, to which the researchers are not yet able to give a complete answer. We know that in the human brain there are about one hundred billion neurons that communicate by means of electrical signals. We learned a lot about the mechanisms of production and transmission of electrical signals among neurons.

Gymnastic feats like balance beam routines clearly require a great deal of coordination. But even seemingly trivial actions such as crossing stepping-stones on a river or just walking in a straight line require these very same skills. The group of Dr. Megan Carey, principal investigator at Champalimaud Centre for the Unknown, has developed a novel tool to investigate how the brain generates coordinated movement.