Cancer chemotherapy has been successful in delaying cancer progression but the flip side has been its side effects. Kinases have gained popularity as drug targets but achieving target specificity is a major bottleneck in the development of anti-cancer drugs. In fact the reason why most of the drugs are shelved during clinical trials is because of their poor therapeutic index. The potential that alternative therapy offers for the treatment of cancer cannot be ruled out, although extensive research has not been performed in this field. A recent article by Lam and colleagues describes the results of herbal medicine used for toxicity induced by chemotherapy. This herb when administered with the drug it stimulates the recovery of intestinal cells, damaged by chemotherapy. Therefore, manmade synthetic drugs along with natural Herbs can be an effective combination therapy to combat cancer.
Ref:_Lam, W. et al. The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity. Sci. Transl. Med. 2, (2010)