It has long been known that type 2 diabetes is linked to obesity, particularly fat inside the belly. Now, researchers at the Joslin Diabetes Center have found that fat from other areas of the body can actually reduce insulin resistance and improve insulin sensitivity.

In a study published in the May issue of Cell Metabolism, a team lead by C. Ronald Kahn, M.D. found that subcutaneous fat -- fat found below the skin, usually in the hips and thighs -- is associated with reduced insulin levels and improved insulin sensitivity.

A new revision of clinical guidelines to help doctors manage patients with depression has challenged the rationale behind the UK government’s policy of rolling out of cognitive behavioural therapy (CBT) for milder depression.

According to a comprehensive review of treatments for depression, there is a lack of evidence for CBT being more helpful than other forms of psychological support in mild depression or for its efficacy in severe depression. There is also good evidence for antidepressants being effective in depression, with benefit increasing the more severe the depression. This is contrary to recent reports that antidepressants don’t work except in the most severe depression.

Dr Ian Anderson, Senior Lecturer and Honorary Consultant Psychiatrist, Neuroscience and Psychiatry Unit, University of Manchester, UK, says the cost effectiveness of CBT should be thoroughly investigated before it is adopted more widely because it is likely to be offered to people with milder depression where the evidence is poorest.

Gambling activity is widespread among U.S. adolescents and young adults ages 14 through 21, according to a study conducted by researchers at the University at Buffalo’s Research Institute on Addictions (RIA).

Results of the first national survey of its kind show problem gambling -- described as gambling with three or more negative consequences (for example, gambling more than you intended or stealing money to gamble) in the past year -- occurring at a rate of 2.1 percent among youth 14 to 21. That ppercentage projects to approximately 750,000 young problem gamblers nationwide.

In addition, 11 percent of the youth surveyed gambled twice per week or more, a rate that describes frequent gambling. Sixty-eight percent of the youth interviewed reported that they had gambled at least once in the past year.

With over half of U.S. children ages 3-6 in child care centers, growing concern over childhood obesity has led physicians to focus on whether children are getting enough physical activity and a new study of outdoor physical activity at child care centers, conducted by researchers at Cincinnati Children’s Hospital Medical Center, has identified some surprising reasons why the kids may be staying inside.

“It’s things we never expected, from flip flops, mulch near the playground, children who come to child care without a coat on chilly days, to teachers talking or texting on cell phones while they were supposed to be supervising the children,” according to Kristen Copeland, M.D., lead author of the study.

Beads known to geologists as carbon cenospheres were formed from liquefied carbon deep in the earth when an asteroid struck some 65 million years ago, according to a new theory.

The carbon cenospheres were deposited next to a thin layer of the element iridium -- an element more likely to be found in Solar System asteroids than in the Earth's crust. The iridium-laden dust is believed to be the shattered remains of the 200-km-wide asteroid's impact. Like the iridium layer, the carbon cenospheres are apparently common. They've been found in Canada, Spain, Denmark and New Zealand.

But the cenospheres' origin presented a double mystery. Cenospheres had been known to geologists only as a sign of modern times -- they form during the intense combustion of coal and crude oil. Equally baffling, there were no power plants burning coal or crude oil 65 million years ago, and natural burial processes affecting organic matter from even older ages -- such as coals from the 300-million-year-old Carboniferous Period -- had simply not been cooked long or hot enough.

Over the past decades competition for fossil fuels and the concern that they are generating large quantities of contaminating gases have given rise to a growing scientific interest in the development of alternative energies.

Most current research is focused on hydrogen cells, the biggest advantages being that they do not generate contaminant gases and have water vapor as the only waste product. However, hydrogen is very expensive, both in production and distribution. It has to be kept and stored under conditions of very high pressure (more than 800 bars).

This is why hydrogen is dangerous and even more so when stored in vehicles travelling at high speed – a small crack in the storage container could have fatal consequences.

X2 Project

X2 Project

May 05 2008 | comment(s)

I was asked by the Institute for the Future to highlight a dozen "Signals" that may point to new trends in science as part of the X2 Project:
Today, science is entering another period of accelerated change, thanks to the growth of the Internet and dawn of pervasive computing; the explosive growth of new sciences like genetic engineering, nanotechnology, biotechnology, and simulation; the rise of new scientific powers in the developing world, the revival of amateur scientists, and the growth of citizen science movements in the United States and Europe; the growth of new institutions supporting scientific research and innovation, and changes in the structure and funding of universities, government, an

Not long ago, Howard Wainer, a statistician I mentioned recently, learned that his blood sugar was too high. His doctor told him to lose weight or risk losing his sight. He quickly lost about 50 pounds, which put him below 200 pounds. He also started making frequent measurements of his blood sugar, on the order of 6 times per day, with the goal of keeping it low.

It was obvious to him that the conventional (meter-supplied) analysis of these measurements could be improved. The conventional analysis emphasized means. You could get the mean of your last n (20?) readings, for example. That told you how well you were doing, but didn’t help you do better.

Howard, who had written a book about graphical discovery, made a graph: blood sugar versus time. It showed that his measurements could be divided into three parts:

Whole-organ maps that superimpose genetic information over the terrain of cancerous bladders chart the molecular journey from normal cell to invasive cancer, an international research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports online ain Laboratory Investigation.

By geographically relating an organ’s varied tissues – normal, precancerous and malignant – to their underlying genetic variation or regulation, the team also identified a crucial new category of genes that launches the process of cancer development.

“These ‘forerunner genes’ are the ignition key that starts the engine of carcinogenesis,” said senior author Bogdan Czerniak, M.D., Ph.D., professor in M. D. Anderson’s Department of Pathology.

Want to live a long life? Your genes still don't make a difference (yet) according to research on the bone health of one of the oldest persons in the world who recently died at the age of 114 The study reveals that there were no genetic modifications which could have contributed to this longevity.

The research team, directed by Universitat Autònoma de Barcelona professor Adolfo Díez Pérez, pointed out a healthy lifestyle, a Mediterranean diet, a temperate climate and regular physical activity as the reasons for his excellent health.

They studied the bone mass and analysed the genetics of a man with enviable health who at the time of the study was 113 years old. The research was carried out with four other members of his family: a 101-year-old brother, two daughters aged 81 and 77, and a nephew aged 85, all of them born and still living in a small town of the island of Menorca. The man's bones were in excellent conditions: his bone mass was normal, there were no anomalous curvatures and he had never sustained a fracture.