Death rates from cancer have been falling for 25 years, but the next generation may cause a tick back up.
Cancer is the second leading cause of death, behind heart disease. Both have age as risk factors but also behavioral components. For cancer, smoking has been the second greatest risk factor overall (and number one for lung cancer) but heart disease is also greatly impacted by fitness. And many cancers can be directly linked to metabolic problems. The current levels of obesity among young people mean that cancer deaths could be at a plateau and set to rise again in 20 years.
Colorectal cancer (CRC) represents an important cause of death, in both developed and developing countries.
APC gene I1307K polymorphism has been particularly associated to an increased risk of this type of cancer in Ashkenazi Jews, while E1317Q polymorphism has been associated to several populations.
The protein complex AMPK is thought to suppress cancer, by slowing cellular metabolism, but it can also help some tumors grow.
But why? A new study says it has solved the mystery.
AMPK acts as a fuel gauge for the cell, overseeing energy input and output to keep the cell running smoothly. Similar to a car sensor flashing a low-gas signal or turning off a vehicle’s AC to save energy, AMPK slows down cell growth and changes the cell’s metabolism if the cell’s fuel (nutrients) is low.
Would famous Apple CEO Steve Jobs be alive today if he had accepted science the same way he accepted technology? Pancreatic cancer will kill half of patients but he guaranteed his death when he waited 9 months after his 2003 diagnosis to have surgery that could have saved his life, instead opting for belief that medicine was bad and alternatives were just as legitimate.
Metastasis is the formation of secondary tumors and a leading contributor to deaths related to cancer. The exact mechanism for how cellular function becomes broken in cells far removed from a cancer’s primary tumor have been unclear.
But it's been pondered for almost a hundred years. It was postulated that metastatic cells spontaneously caused secondary tumors by fusing their cellular material with regular cells and re-establishing their errant gene expression, but spontaneous is not a concept scientists like, so the search for the real causes has been ongoing.
A review of data on nearly 20 million people has concluded
that having diabetes significantly raises the risk of developing cancer.
For women the risk is even higher, not just of cancer but also leukemia and cancers of the stomach, mouth and kidney. Men, however, had less risk for liver cancer. If none of that makes sense, you see the flaws in replacing science with epidemiological statistics.
The International Agency for Research on Cancer (IARC), which operates under the auspices of the U.N. World Health Organisation, is soliciting comments prior to holding an Advisory Group meeting in November to propose revisions to its Preamble.
There are many different types of human papilloma virus (HPV). Some are associated with the development of cervical lesions that can become cancerous and are considered as high-risk HPV types. Two of these high-risk types (HPV16 and HPV18) account for about 70% all cases of cervical cancer worldwide.
Most people who have sexual contact at some point in their life will be exposed to HPV. In the majority of women, HPV infection will be cleared by the immune system but when the immune system does not clear the virus, persistent HPV infection may lead to abnormal cervical cells which can progress to cervical cancer if left untreated.
Cancer has always been thought of as something that grows rapidly and uncontrollably, but this view may be wrong.
New evidence suggests that cancer alternatively uses the “accelerator” and the “brake” in order to survive.
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