Cancer Research

Metastasis is the formation of secondary tumors and a leading contributor to deaths related to cancer. The exact mechanism for how cellular function becomes broken in cells far removed from a cancer’s primary tumor have been unclear.

But it's been pondered for almost a hundred years. It was postulated that metastatic cells spontaneously caused secondary tumors by fusing their cellular material with regular cells and re-establishing their errant gene expression, but spontaneous is not a concept scientists like, so the search for the real causes has been ongoing.
A review of data on nearly 20 million people has concluded that having diabetes significantly raises the risk of developing cancer.

For women the risk is even higher, not just of cancer but also leukemia and cancers of the stomach, mouth and kidney. Men, however, had less risk for liver cancer. If none of that makes sense, you see the flaws in replacing science with epidemiological statistics.

The International Agency for Research on Cancer (IARC), which operates under the auspices of the U.N. World Health Organisation, is soliciting comments prior to holding an Advisory Group meeting in November to propose revisions to its Preamble.

There are many different types of human papilloma virus (HPV). Some are associated with the development of cervical lesions that can become cancerous and are considered as high-risk HPV types. Two of these high-risk types (HPV16 and HPV18) account for about 70% all cases of cervical cancer worldwide.

Most people who have sexual contact at some point in their life will be exposed to HPV. In the majority of women, HPV infection will be cleared by the immune system but when the immune system does not clear the virus, persistent HPV infection may lead to abnormal cervical cells which can progress to cervical cancer if left untreated. 

Cancer has always been thought of as something that grows rapidly and uncontrollably, but this view may be wrong.
New evidence suggests that cancer alternatively uses the “accelerator” and the “brake” in order to survive.

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The world’s second densest metal can be used to kill cancer cells by filling them with a deadly version of oxygen, without harming healthy tissue, according to a new paper.

The metal, iridium, was in the asteroid with the strongest link to the extinction of dinosaurs. When combined with organic material, the researchers showed it can be directly targeted towards cancerous cells, transferring energy to the cells to turn the oxygen (O2) inside them into singlet oxygen, which is poisonous and kills the cell - without harming any healthy tissue.

There are reasons to get an HPV vaccine - it literally prevents cancer - but consumer marketing is misstating absolute and relative risk when it comes to throat cancer. A preventive vaccine against HPV types, 6, 11, 16, and 18 has been in widespread use for a decade, and a version that also protects against five other HPV types was FDA-approved in 2014. Those vaccines won't clear existing HPV infections.

Fibrolamellar hepatocellular carcinoma, a form of liver cancer mainly found among children and young people, currently has surgery as the only treatment available. But even then less than 40 percent of patients will survive beyond five years.

It might help to discover what causes it.

Even small tumors can be aggressive, according to a study in patients with early stage breast cancer presented at the ESMO 2017 Congress in Madrid.  They found that nearly one in four small tumors were aggressive and patients benefited from chemotherapy. Aggressive tumors could be identified by a 70-gene signature.