The effectiveness of e-cigarettes as a smoking substitute will likely rely on whether they can consistently provide the amount of nicotine a smoker needs to resist the desire to return to traditional cigarettes.
A recent study that evaluated a new method for measuring nicotine delivery from e-cigarettes found that 'first-generation' e-cigarettes, which use 'cartomizers', deliver nicotine less consistently than later-generation e-cigarettes, which use 'atomizers' that vaporize liquid contained in a refillable tank.
The consistency of nicotine delivery from the atomizers was similar to nicotine inhalers and tobacco cigarettes and within the acceptable limits for medicinal nebulizers.