New evidence that genetics plays a key role in obesity is published today in the International Journal of Bioinformatics Research and Applications. The findings relate to the genetics of modern Pima Indians who have an unusually high rate of obesity but could be extrapolated to all people. Their obesity is thought to be linked to a thrifty metabolism that allowed them to metabolize food more efficiently in times when little was available but causes problems when food is in abundance.
Mark Rowe, David McClellan, and colleagues at Brigham Young University in Provo, Utah, USA, have studied the effect of evolutionary selection on Pima Indians, a people indigenous to the present-day Sonora desert of Arizona and New Mexico.