Malnourished children are most likely to die from common infections, not starvation alone, and immune disorder may be part of the cause, according to a review led by Queen Mary University of London.
The paper, published in Trends in Immunology, also indicates that even with a healthy diet, defects in immune system function from birth could contribute to a malnourished state throughout life. These altered immune systems could be passed down from generation to generation regardless of the diet of any offspring.
Researchers speculate that targeting immune pathways could be a new approach to reduce the poor health and mortality caused by under- and overnutrition.