It used to be common to hear criticism about the FDA not approving new drugs fast enough, usually something that had been 'used in Europe' without issue.

That changed in 2004 with the Clinical Trials Directive, which came into force in May of that year in order to create a harmonized framework for clinical drug research across Europe, and some academics say it will make European schools also-rans in the research community.

Many sponsor organisations, commercial and non-commercial alike, have criticised the Directive for the enormous increase in administrative burdens and cost that complying with it imposes.

Sociology studies often contend that crime rate and budget alone do not account for the size of an area’s police force.

Police forces tend to be larger in areas where blacks comprise a larger percentage, and many sociologists have attributed this to racial attitudes, specifically the white population’s perceptions of threat.

A new study attempts to empirically examine this premise and concluded that while direct measures of anti-black prejudice are not correlated to police size, whites’ fear of crime and perceived economic threat still somehow account for more than one-third of the effect of the proportion of black residents on police force size. No evidence but they are still sure it must be true?

Welcome to modern sociology.

A report(1) released today by the Eurasian Harm Reduction Network (EHRN)(i) highlights the significant inconsistencies that exist in hepatitis C (HCV) diagnosis and treatment across Europe and beyond. In recognition of World Hepatitis Awareness Day, patient groups around the globe are united in their call for action.

The report indicates that in some European countries it is estimated that more than 90% of people who are infected with HCV have not been diagnosed (Germany 90%; Poland 98%)(ii). Not only does this put many people at risk of long-term liver damage, it also means that they may unknowingly transmit the virus to others.

The first step in the development of colon cancer is the formation of benign tumours, called adenomas, in the intestine. Over time, these tumours may progress to produce colon cancer if they undergo a series of mutations and genetic alterations.

Researchers at IRB Barcelona under the direction of Eduard Batlle, ICREA researcher and head of IRB Barcelona’s Oncology Programme, have discovered a new mechanism by which the benign tumour cells receive instructions to grow in confined compartments, and no to invade other areas of the tissue. The description of this new tumour suppression mechanism is reported in Nature Genetics.

Tiny pieces of genetic material called microRNA (miRNA), better known for its roles in cancer, could be a key to unlocking the secrets of how HIV, the AIDS virus, evades detection, hiding in the immune system. Researchers at Jefferson Medical College in Philadelphia have shown that when an individual infected with HIV receives a powerful cocktail of antiviral agents called HAART (highly active antiretroviral therapy), the virus calls on miRNAs to help it remain quiet and practically undetectable, temporarily shutting down its ability to replicate and infect.

The work may also have implications for new treatment strategies against the virus.

Countries where the main religion is Protestant Christianity have higher employment rates than those where other religions are dominant, according to University of Bath research published in the American Journal of Economics and Sociology.

These countries, which include the USA, the UK and Nordic countries such as Denmark, Sweden and Norway, have employment rates that are approximately six percentage points higher than countries where other religions are practiced by the largest proportion of the population.

The study, which is based on data from 80 countries, also showed that female employment rates are approximately 11 percentage points higher in Protestant countries.

When a child is distressed, anxious, or angry, mom and dad don’t have to respond in the same way. A new study finds that when both parents are supportive, they may shield the child from handling negative emotions.

The researchers suggest that when one parent provides little support and the other provides more support—for example, if a child becomes anxious or upset about losing a favorite toy, one parent may intervene by hugging the child and helping think of places to look for the toy, while the other parent hangs back and is available if needed—the child ends up with reduced conflicts with friends and a better understanding of negative emotions.

Determining the genetic profile of a particular lung tumor can help clinicians make the crucial decision about which chemotherapy treatment to try first.

A new study led by researchers from the Duke University Comprehensive Cancer Center and the Duke Institute for Genome Sciences & Policy (IGSP) found distinct differences in the susceptibility different tumors have to widely used chemotherapy drugs.

“We were able to predict which tumors would be most likely to respond to standard first-line therapy and which would respond better to what has traditionally been a second-line therapy, based on gene expression profiling,” said David Hsu, M.D., Ph.D. an oncologist at Duke and lead author on the publication. “This represents a big step in the move toward individualized medicine.

Materials researchers at the National Institute of Standards and Technology (NIST), together with colleagues from IBM and the Massachusetts Institute of Technology, have pushed the measurement of thin films to the edge—literally—to produce the first data on how the edges of metallic thin films contribute to their magnetic properties. Their results may impact the design of future nanoscale electronics.

Ferromagnetic thin films of metallic materials—ranging in thickness from fractions of a nanometer to several micrometers—are layered in patterns on a substrate (such as silicon) during the manufacture of many microelectronic devices that use magnetic properties, such as computer hard drives.