Thanks to government mandates and ongoing subsidies, wind energy has become more popular, and one impact of large-scale wind energy development has been widespread mortality of bats. A new study tracks down the origin of bats killed by wind turbines in the Appalachian region in hopes of better understanding the risks to affected populations.

Individuals with 2p15p16.1 microdeletion syndrome present with intellectual disability, microcephaly, delayed growth, dysmorphic craniofacial features, and digital abnormalities. The precise genetic region responsible for this syndrome has been challenging to identify. However, recent reports indicate that 4 genes (XPO1, USP34, BCL11A, and REL) are commonly deleted in this syndrome. A study in the current issue of JCI Insight describes 8 new subjects with microdeletions in chromosomal region 2p15p16.1 and provides evidence that loss of XPO1, REL, and BCL11A underlie this syndrome.

Bladder cancer is the fourth most common cancer among men in the United States. While low-grade tumors have a very favorable prognosis, muscle-invasive and metastatic tumors have poorer survival rates. In this month's issue of JCI Insight, William Kim, Benjamin Vincent, and a research team from the University of North Carolina characterized a new subtype of muscle-invasive bladder cancer that shares molecular signatures with some forms of breast cancer. A subset of triple-negative breast cancers express low levels of the tight junction protein claudin. The UNC researchers now document that claudin-low tumors represent a specific subtype of bladder cancer as well.

Antibody-secreting plasma cells arise from B cell precursors and are essential for adaptive immune responses against invading pathogens. Plasma cell dysfunction is associated with autoimmune and neoplastic disorders, including multiple myeloma. Surface markers that are specific to plasma cells have not been identified and antibodies that only recognize these cells have been challenging to generate using conventional systems. In the current issue of JCI Insight, Götz Ehrhardt and colleagues at the University of Toronto describe the generation of a plasma cell-specific antibody from immunized lampreys.

 Minority applicants may fare even worse in the resume pile at companies purporting to support diversity than they would at companies that don't make the claim, shows a new study from the University of Toronto.

That's because job seekers are less likely to "whiten" their resumes by downplaying their racial identities when responding to pro-diversity job ads. The odds of getting a callback for an interview when resumes are not whitened are significantly worse, regardless of whether the company says it's a pro-diversity employer or not. On the other hand, hiding one's race by "whitening" was found to improve minorities' chances of landing an interview.

MINNEAPOLIS - Women may have a better memory for words than men despite evidence of similar levels of shrinkage in areas of the brain that show the earliest signs of Alzheimer's disease, according to a study published in the March 16, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

DALLAS, March 16, 2016 -- A healthy heart may have major benefits for preventing the decline in brain function that sometimes accompanies aging, according to new research in Journal of the American Heart Association.

Researchers studied a racially diverse group of older adults and found that having more ideal cardiovascular health factors was associated with better brain processing speed at the study's start and less cognitive decline approximately six years later.

The researchers from the University of Miami and Columbia University used the American Heart Association's "Life's Simple Seven®" definition of cardiovascular health, which includes tobacco avoidance, ideal levels of weight, physical activity, healthy diet, blood pressure, cholesterol and glucose.

In an article published in the March 2016 issue of the Journal of Anxiety Disorders, investigators in the Department of Psychiatry and Behavioral Sciences at the Medical University of South Carolina (MUSC) report that veterans who fall just below the threshold for a diagnosis of post-traumatic stress disorder (PTSD) respond to a psychotherapy regimen better than those with full PTSD. The study highlights the need to recognize veterans suffering from an overlooked condition called subclinical PTSD.

DARIEN, IL - A new study is the first to report that the relationship between nightmares and suicidal behaviors is partially mediated by a multi-step pathway via defeat, entrapment and hopelessness.

Gender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia have been revealed for the first time in a study published in the open access journal Molecular Brain.

While previous studies have shown that women exhibit higher risk of dementia than men, the underlying mechanisms of this gender difference have remained elusive. The findings by researchers from Nanyang Technological University, Singapore may advance our understanding of the higher risk of dementia that has been observed in women compared to men, which the researchers suggest could lead to the development of new drugs for dementia treatment.