An international consortium of scientists has identified multiple genes that are linked to systemic lupus erythematosus, a devastating autoimmune disease that affects between 1 million and 2 million Americans. Reporting in Nature Genetics, the scientists also confirmed earlier findings linking lupus to several other genes – highlighting the role that genetics plays in the disease.

“These findings underscore that numerous genes, which are often immune-function related, contribute to the risk of developing lupus,” said Carl D. Langefeld, Ph.D., senior author from Wake Forest University School of Medicine and co-director of the International Consortium for Systemic Lupus Erythematosus Genetics (www.SLEGEN.org).

Friendships are an important part of developing social skills and cultural confidence but when antisocial teenagers interacted closely with each other and spent their time discussing such things as substance abuse or breaking the law, they tended to later engage in problem behavior, according to University of Oregon researchers.

For their study, the researchers videotaped 16- and 17-year-olds as they interacted with close friends. The UO team was seeking to find mechanisms behind the idea that antisocial behavior is predictable based on the behavior of peers.

A new study by the Kaiser Permanente Division of Research says that women should avoid caffeine during the first trimester of pregnancy - caffeine equivalent to two cups of coffee per day was linked to a doubled risk of miscarriage compared to women who had no caffeine.

The study controlled, for the first time, pregnancy-related symptoms of nausea, vomiting and caffeine aversion that tended to interfere with the determination of caffeine’s true effect on miscarriage risk. The research appears in the current online issue of American Journal of Obstetrics and Gynecology.

Plasticity, the brain's ability to change in response to its environment, is at the heart of learning. After being awake, your brain needs sleep to refresh, research says.

A new theory from University of Wisconsin-Madison researchers Dr. Chiara Cirelli, associate professor of psychiatry, and Dr. Giulio Tononi, professor of psychiatry, called the synaptic homeostasis hypothesis, runs against the grain of what many scientists currently think about how sleep affects learning. The most popular notion these days, says Cirelli, is that during sleep synapses are hard at work replaying the information acquired during the previous waking hours, consolidating that information by becoming even stronger.

Dark-field images provide more detail than ordinary x-ray radiographs and could be used to identify explosives in hand luggage, diagnose the onset of breast cancer or Alzheimer’s disease and pinpoint hairline cracks or corrosion in functional structures.

The issue has been that the wavelengths needed for dark-field images required sophisticated optics that could only be produced at facilities like the Paul Scherrer Institute (PSI)’s 300m-diameter, $200 million synchrotron. Now researchers at PSI and Ecole Polytechnique Fédérale de Lausanne in Switzerland have developed a novel method allowing dark-field images to be produced using ordinary x-ray equipment already in place in hospitals and airports around the world.

The first evidence of a volcanic eruption from beneath Antarctica’s most rapidly changing ice sheet is reported this week in the journal Nature Geosciences. The volcano on the West Antarctic Ice Sheet erupted 2000 years ago (325BC) and remains active.

Using airborne ice-sounding radar, scientists from British Antarctic Survey (BAS) discovered a layer of ash produced by a ‘subglacial’ volcano. It extends across an area larger than Wales.

The volcano is located beneath the West Antarctic ice sheet in the Hudson Mountains at latitude 74.6°South, longitude 97°West. Volcanoes are an important component of the Antarctic region. They formed in diverse tectonic settings, mainly as a result of mantle plumes acting on the stationary Antarctic plate.

Using embryonic stem cells from mice, UT Southwestern Medical Center researchers have prompted the growth of healthy – and more importantly, functioning – muscle cells in mice afflicted with a human model of Duchenne muscular dystrophy.

The study represents the first time transplanted embryonic stem cells have been shown to restore function to defective muscles in a model of muscular dystrophy.

The researchers’ newly developed technique, which involves stringent sorting to preserve all stem cells destined to become muscle, avoids the risk of tumor formation while improving the overall muscle strength and coordination of the mice, the researchers found.

Scientific studies on climate change, energy and alternative fuels are among the 30 projects awarded more than 145 million processing hours on supercomputers at Oak Ridge National Laboratory through the Department of Energy's Innovative and Novel Computational Impact on Theory and Experiment (INCITE) program.

Through INCITE, researchers from industry, academia and government research facilities receive access to computing power at the National Center for Computational Sciences at ORNL for research on climate change, fusion energy, nanoscience, materials, chemistry, astrophysics, and other areas.

Raptor 03, the third F-22 manufactured by the team of Lockheed Martin, Boeing and Pratt & Whitney is now part of a new exhibit at The National Museum of the U.S. Air Force. One of nine F-22s built for engineering, manufacture and development testing, Raptor 03 will remain on display in the museum.

The F-22 was the winner of the Advanced Tactical Fighter (ATF) contract, a "stealth fighter" designed to replace the F-15 Strike Eagle and surpass the capabilities of Soviet-era Su-27 "Flanker"-class fighter aircraft.

Raptor 03 was the test fleet workhorse. It was used for loads testing, crosswind landing trials, arrester hook evaluations,and weapons bay environment studies.

The odometer of a low emission hybrid electric test vehicle today reached 100,000 miles as the car circled a track in the UK using the power of an advanced CSIRO battery system.

The UltraBattery combines a supercapacitor and a lead acid battery in a single unit, creating a hybrid car battery that lasts longer, costs less and is more powerful than current technologies used in hybrid electric vehicles (HEVs).

“The UltraBattery is a leap forward for low emission transport and uptake of HEVs,” said David Lamb, who leads low emissions transport research with the Energy Transformed National Research Flagship. “Previous tests show the UltraBattery has a life cycle that is at least four times longer and produces 50 per cent more power than conventional battery systems.