New treatments for infertility could be closer to reality, thanks to a discovery from scientists at the Université de Montréal and Maisonneuve-Rosemont Hospital Research Centre.

According to a study published in the journal Molecular Human Reproduction, the researchers have become the first to clone, produce and purify a protein important for sperm maturation, termed Binder of Sperm (BSP), which may have implications for both fertility treatments and new methods of male contraception.

Half-biological and half-synthetic, an army of thousands of wrecking balls are contained within Dr. Metin Sitti's Carnegie Mellon laboratory.  Once incited, they keep moving to the death.  They run on sugar.  And they can all be taken down by penicillin. 

Sitti’s army is a cadre of Serratia marcensens bacteria-coated polystyrene microbeads, propelled by the bacteria’s innate restlessness.  To Sitti, recruiting bacteria to form the propulsion side of a microprojectile is more than a fun day in the lab.  These tiny living robots are the foundation for the future of biointegrated micromachines.

Professor Lynn Margulis is the biologist who had the incredible insight that the cells of modern organisms were originally formed by the symbiotic combination of prokaryotic cells and colonies of bacteria, and then had to battle for years to have this recognised by the science community.

The idea is so outlandish, but so significant, that it puts her right up there as one of the greats of biology.

To look at Matthew Houdek, you could never tell he was born with virtually no left ear.

A surgery at Loyola University Health System made it possible for Houdek to be fitted with a prosthetic ear that looks just like the real thing.

Ear-nose-throat surgeon Dr. Sam Marzo implanted three small metal screws in the side of Houdek's head. Each screw is fitted with a magnet, and magnetic attraction holds the prosthetic ear in place.

It takes only a few seconds for Houdek to put his prosthetic ear on in the morning and take it off when he showers or goes to bed. It doesn't fall off, and it's much more convenient than prosthetic ears that are attached with adhesive. 

Humans excel at recognizing faces, but how we do this has been an abiding mystery in neuroscience and psychology. In an effort to explain our success in this area, researchers are taking a closer look at how and why we fail. 

A new study from MIT looks at a particularly striking instance of failure: our impaired ability to recognize faces in photographic negatives. The study, which appears in the Proceedings of the National Academy of Sciences this week, suggests that a large part of the answer might lie in the brain's reliance on a certain kind of image feature.

FINDINGS: Scientists at the Whitehead Institute for Biomedical Research and the National University of Singapore have discovered the first microRNA (miRNA) capable of directly tamping down the activity of the well known tumor-suppressor gene, p53, While p53 functions to prevent tumor formation, the p53 gene is thought to malfunction in more than 50% of cancerous tumors.

RELEVANCE: The study reports the first time a miRNA has been shown to directly affect the p53 protein level, although researchers have previously identified other genes and miRNAs that indirectly affect p53's activity.

A group of international researchers has found the first reliable evidence that early detection of subsequent breast tumours in women who have already had the disease can halve the women's chances of death from breast cancer.

According to the research published online today (Wednesday 18 March) in the cancer journal, Annals of Oncology [1], if the second breast cancer was picked up at its early, asymptomatic stage, then the women's chances of survival were improved by between 27-47% compared to women whose second breast cancer was detected at a later stage when symptoms had started to appear.

In the past few years, a number of anti-cancer drugs have been developed which are directed selectively against specific key molecules of tumor cells. Among these is an antibody called cetuximab, which attaches to a protein molecule that is found in large amounts on the surface of many types of cancer cells. When this surface molecule, called epidermal growth factor receptor, or EGF-R for short, is blocked by cetuximab, the cancer cell receives less signals stimulating cell division.

"Asking for help is a universally dreaded endeavor,"  M. Nora Klaver says in her anti-self-help book, "Mayday! Asking for help in times of need. Seven out of ten people admit they could have used help over the last week but didn't ask for it. Klaver reveals the myriad of reasons why we don't ask for help, how we can benefit from asking, and how to ask the right people at the right time in the right place, increasing our opportunities for meeting our needs.

I'll admit I'm a Plutophile. Whether it's called a planet or not, it's a very interesting place. Yet despite sending New Horizons to visit it (fastest launch ever!), despite the discovery of other Kuiper Belt objects, one facet of Pluto continues to dominate the news. Is it a planet? As it turns out, there are things far more important to consider about Pluto than its planethood status.