In epilepsy, nerve cells or neurons lose their usual rhythm, and ion channels, which have a decisive influence on their excitability, are involved. A team of researchers under the direction of the University of Bonn has now discovered a new mechanism for influencing ion channels in epilepsy. They found that spermine inside neurons dampens the neurons excitability. In epilepsy, spermine levels decrease, causing hyperexcitability. The researchers hope that their findings can be exploited to develop new therapies for epilepsies. They are reporting their findings in "The Journal of Neuroscience".

Discussions of the ethics of terraforming often touch on  rights of planets or extraterrestrial lifeforms, or near term utilitarian values. But what about our responsibilities to terraformed worlds, and their long term future? I suggest that we are nowhere near mature enough as a civilization to be responsible parents to a newly terraformed world with a gestation period of millennia and an "adult life" of hundreds of millions of years.

Attention Deficit Hyperactivity Disorder (ADHD) is one of the most commonly diagnosed childhood disorders and can continue through adolescence into adulthood. Diagnoses exploded in the 1990s and now it is found in about 5% of children, but such diagnosis is based on clinical judgment rather than objective diagnostic markers. Symptoms include difficulty focusing attention and remaining "on task", impulsive behavior and extreme hyperactivity but some diagnoses have been made even when those behaviors were mild, so chemical interventions should be cautiously - but they are not.

Neural tube defects in Europe remain too high for the past 20 years, despite a long-standing medical recommendation that would prevent them, according to a paper in The BMJ today. 

Each year, around 5,000 pregnancies in Europe are affected by neural tube defects like spina bifida and anencephaly (problems with brain and skull formation), with serious consequences for newborns and their families. Taking folic acid supplements before and during early pregnancy can greatly reduce the risk, but evidence suggests that only a small minority of women do so.

The speed and character of human dispersals changed significantly around 100,000 years ago, and our dark side deserves a thanksgiving for that; a new paper suggests that betrayals of trust were the missing link in understanding the rapid spread of our species around the world. 

VY Canis Majoris is a stellar goliath, a red hypergiant, one of the largest known stars in the Milky Way. It is 30-40 times the mass of the Sun and 300 000 times more luminous. In its current state, the star would encompass the orbit of Jupiter, having expanded tremendously as it enters the final stages of its life.

Drowning has emerged as a mysterious cause of death amongst groups of young common starlings (Sturnus vulgaris), according to research by a team of scientists led by international conservation charity the Zoological Society of London (ZSL).

Drowning as a cause of death amongst wild birds is comparatively rare and normally involves single rather than multiple animals. Starlings, however, have been observed to drown in groups of 10 or more, prompting scientists to investigate these unusual occurrences.

Boulder, Colo., USA - Whether extreme river floods are becoming more frequent and/or severe in a warming world remains under debate, partly because instrumental measurements of river discharge are too restricted in length to detect shifts from natural variability. In this open access article for Geology, Daniel Schillereff and colleagues demonstrate for the first time the recovery in a systematic manner of flood frequency and magnitude data from temperate lakes that accumulate homogeneous (visually similar) sediments.

Researchers at a breast cancer prevention clinic in Manchester have observed an increased uptake of preventative double mastectomies since May 2013, when Angelina Jolie announced that she had undergone the procedure.  

Researchers from the Genesis Prevention Centre Family History clinic report that the number of preventative double mastectomies performed after consultation at the clinic more than doubled from January 2014 to June 2015, with 83 procedures performed during this period, compared to 29 between January 2011 and June 2012.  

Montreal, November 24, 2015 -- As world leaders prepare to gather in France for the 2015 United Nations Conference on Climate Change next week, global warming -- and how to stop it -- is a hot topic.

To limit climate change, experts say that we need to reach carbon neutrality by the end of this century at the latest. To achieve that goal, our dependence on fossil fuels must be reversed. But what energy source will take its place? Researchers from Concordia University in Montreal just might have the answer: algae.