ROANOKE, Va., Nov. 16, 2015 - Scientists from the Virginia Tech Carilion Research Institute and clinicians from Carilion Clinic have discovered how to sensitize drug-resistant human glioblastoma cells to chemotherapy.

They published their results in Cancer Research, the scientific journal of the American Association of Cancer Research.

Glioblastoma accounts for almost half of all brain cancers. Fewer than one in 20 patients survive five years after their diagnosis, and treatment involves surgical removal of the cancerous tissue, followed by chemotherapy.

A team of Belgian researchers has shown that the yeasts used to ferment cocoa during chocolate production can modify the aroma of the resulting chocolate. "This makes it possible to create a whole range of boutique chocolates to match everyone's favorite flavor, similar to wines, tea, and coffee," says Jan Steensels, a postdoctoral researcher at the University of Leuven, and the Flanders Institute for Biotechnology, Belgium.  

Due to disease-related changes in their brain, pain patients often suffer from an impaired tactile ability in their hands. In a pilot study conducted by scientists at the Ruhr-University Bochum, high frequency repetitive stimulation was investigated as a therapeutic approach for these patients. The results of this study have now been published in the journal "Frontiers in Neurology". They show that passive stimulation of this kind is a promising new therapy option.


Passive stimulation: a proven therapy approach


You were once a hollow shell. To sculpt that hollow ball into an organism with layers of internal organs, muscle and skin, portions of that embryonic 'shell' folded inwards. The same happens to fruit fly embryos, and researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have now identified a particular group of cells which are crucial for the first such fold. They also showed for the first time that the shape in which cells are arranged determines the direction in which they contract. Published today in Developmental Cell, the findings were obtained thanks to a new technique in which the scientists use a laser as a remote control.

Warming temperatures will take a heavy toll on agricultural productivity, according to climate scientists. How will society adjust? One possibility might be increased trade: If one country suffers a decline in, say, wheat production but can still grow as much rice as ever, then -- in theory -- it might grow more rice and trade for its usual amount of wheat instead.

But a new study co-authored by an MIT economist suggests that international trade will do little to alleviate climate-induced farming problems. Instead, the report indicates that countries will have to alter their own patterns of crop production to lessen farming problems -- and even then, there will be significant net losses in production under the basic scenarios projected by climate scientists.

CHAMPAIGN, Ill. -- As the export of wood pellets from the U.S. to the European Union has increased six-fold since 2008, questions have been raised about the environmental impact of the practice. According to a new paper from a University of Illinois expert in environmental economics, even after accounting for factors ranging from harvesting to transportation across the Atlantic Ocean, wood pellets still trump coal by a wide margin in carbon emissions savings.

The greenhouse gas intensity of wood pellet-based electricity is between 74 to 85 percent lower than that of coal-based electricity, says published research co-written by Madhu Khanna, a professor of agricultural and consumer economics at Illinois.

Researchers are reporting a breakthrough toward developing an artificial pancreas as a treatment for diabetes and other conditions by combining mechanical artificial pancreas technology with transplantation of islet cells, which produce insulin.

In a study of 14 patients with pancreatitis who underwent standard surgery and auto-islet transplantation treatments, a closed-loop insulin pump, which relies on a continuous cycle of feedback information related to blood measurements, was better than multiple daily insulin injections for maintaining normal blood glucose levels.

The armored shells of some marine mollusks have evolved to satisfy two conflicting design requirements, protection and sight, a new study shows.

Kids and teens who take medications like Ritalin to treat attention-deficit hyperactivity disorder are also twice as likely to be physically or emotionally bullied by peers. At even higher risk were middle and high school students who sold or shared their medications--those kids were four-and-a-half times likelier to be victimized by peers.

The main findings are the same for both sexes, said the study's first author, Quyen Epstein-Ngo, research assistant professor in gender studies at the University of Michigan. 

I was very happy today to sign a contract with an international publisher that will publish a book I have written. The book, titled "Anomaly! - Scientific Discoveries and the Quest for the Unknown", focuses on the CDF experiment, a particle detector that operated at the Tevatron collider for 30 years. 
The Tevatron was the highest-energy collider until the turn-on of the LHC. The CDF and DZERO experiments there discovered the sixth quark, the top, and produced a large number of world-class results in particle physics.