After a 30-year search, scientists have uncovered how an enzyme critical to plants' rapid immune response against microbes is activated.

"The insights will open up new ways to improve disease resistance and stress tolerance in plants," says Professor Cyril Zipfel of The Sainsbury Laboratory in Norwich.

The enzyme, the NAPDH oxidase RBOHD, triggers a rapid generation of signalling molecules derived from oxygen that are believed to be detrimental to microbial growth. The newly-discovered way this enzyme is activated, by a protein (called BIK1) fills a gap in how plants perceive a threat and how signals are activated to trigger an immune response.

Washington, DC— John F. Strang, PsyD, a pediatric neuropsychologist at Children's National Health System, and colleagues, found that children with autism spectrum disorders (ASD) or attention deficit hyperactivity disorder (ADHD) were more likely to exhibit gender variance, the wish to be the other gender, than children with no neurodevelopmental disorder, or a medical neurodevelopmental disorder such as epilepsy or neurofibromatosis.

Will one-atom-thick layers of molybdenum disulfide, a compound that occurs naturally in rocks, prove to be better than graphene for electronic applications? There are many signs that might prove to be the case. But physicists from the Faculty of Physics at the University of Warsaw have shown that the nature of the phenomena occurring in layered materials are still ill-understood and require further research.

NEW ORLEANS─The number of total knee replacement (TKR) procedures continues to climb, as does the number of revision total knee replacement (RTKR) surgeries. In the study, "The Epidemiology of Revision Total Knee Arthroplasty in the United States," presented today at the 2014 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), researchers used the Nationwide Inpatient Sample (NIS) to evaluate the cause of knee failure for 301,718 revision RTKR surgeries performed between 2005 and 2010.

Poisoning of dingoes - wild dogs - has a deleterious effect on small native mammals such as marsupial mice, bandicoots and native rodents, according to a new paper which found that loss of dingoes after baiting is associated with greater activity by foxes, which prey on small marsupials and native rodents.

As well, the number of kangaroos and wallabies increases when dingoes, the top predators in the Australian bush, disappear. Grazing by these herbivores reduces the density of the vegetation in which the small ground-dwelling mammals live.

The instant gratification and the pleasure derived from consuming excessive chocolate and deep-fried foods can lead way to a double-edged sword of negative consequences ranging from weight gain to feelings of low self-esteem. According to a new study in the Journal of Consumer Research, combating this type of self-destructive behavior may be achieved simply by making a person feel sad.

"We found that when people who are sad are exposed to pictures of indulgent food or indulgent words, their sadness highlights the negative consequences of indulging and encourages them to indulge less," write authors Anthony Salerno, Juliano Laran (both University of Miami), and Chris Janiszewski (University of Florida).