The sonic hedgehog gene, best known for controlling embryonic development, also maintains the normal physiological state and repair process of an adult healthy lung, if damaged, according to new research. 

Tissues are not all created equal in their ability to regenerate. Skin and blood cells are continually turning over, making entirely new populations of cells every few days. At the other end of the spectrum, heart and brain cells regenerate slowly, if at all, after injury. Between these two extremes are tissues such as the lung and liver, which have little cellular turnover in normal adults, but can regenerate extensively after injury. Such tissues, overall, are thought to be quiescent.

An enhanced inflammatory response could be the key link between high saturated fat intake - a recognized risk factor for obesity-related disorders - and the development of diseases like type 2 diabetes and atherosclerosis.

A new study in the Journal of Nutritional Biochemistry demonstrates that ingesting fats similar to those in a Mediterranean-type diet, featuring low saturated fat and high monounsaturated fat, appears to decrease the inflammatory response, both in comparison to a high saturated fat diet, as well as in relation to a low-fat diet.

Goldenrod, Himalayan balsam, Chinese windmill palm: three plants, one problem. All are native to continents other than Europe, but were introduced to Switzerland as garden or ornamental plants. At some point they "escaped" into the wild, where they now threaten the native flora.

This phenomenon isn't limited to Switzerland: biological invasions happen on every continent every day. A major driver of this is global trade, which is increasingly shifting to the internet and being conducted on auction platforms like eBay. As a result, one click is all it takes to spread potentially invasive plants from continent to continent - and unintentionally encouraging biological invasions.

Monitoring online auctions

More than half (53 percent) of U.S. consumers want to know what’s in their DNA, according to a new survey, yet only 7 percent of respondents say that their doctor has discussed genetic screening with them.

The nationwide survey, conducted by marketing research company ORC International among a representative sample of 1,020 adults, explored knowledge of and attitudes toward genetic testing among adult consumers. The strong interest in genetic screening that is evident from the survey can be attributed to a variety of factors, but may point to an interest among consumers in using genetic screening to be more proactive about their healthcare.

When cells from the connective tissue collide, they repel one another - this phenomenon was discovered more than 50 years ago. It is only now, however, that researchers at the University of Basel have discovered the molecular basis for this process, as they report in the journal Developmental Cell. Their findings could have important implications for cancer research.

Fibroblasts are motile constituents of the connective tissue and also regulate its stiffness. Moreover, fibroblasts play an important role in malignant skin diseases such as melanoma. In research, they serve as a model system for studying cell migration.

Signaling pathway identified