Scientists' hunt for the cause of depression has implicated so many suspects and found so many treatments with different mechanisms that the condition remains an enigma. Now researchers at the Stanford University School of Medicine have identified one unifying principle that could explain how a range of causes and treatments for depression converge.

They found that in rats the differing mechanisms of depression and its treatment in the end appear to funnel through a single brain circuit. Changes in how the electrical signals spread through the circuit appear to be the cause of depression-related behavior, according to their study.

New research led by University of New Hampshire physicists has proved the existence of a new type of electron wave on metal surfaces: the acoustic surface plasmon, which will have implications for developments in nano-optics, high-temperature superconductors, and the fundamental understanding of chemical reactions on surfaces. The research, led by Bogdan Diaconescu and Karsten Pohl of UNH, is published in the July 5 issue of the journal “Nature.”

“The existence of this wave means that the electrons on the surfaces of copper, iron, beryllium and other metals behave like water on a lake’s surface,” says Pohl, associate professor of physics at UNH. “When a stone is thrown into a lake, waves spread radially in all directions.

For some years now, scientists throughout the world have been in a position to use the complete base sequence of the human genome for their analyses.

A question often encountered is whether or not specific sequence motifs have a special function. This is likely in cases where the motif is found in a particular place more often than mere chance distribution would suggest. So far, such calculations have only been possible using time-consuming computer simulations.

Increased exposure to common chemicals may impact ovarian development, says Dr. Paul Fowler, of the University of Aberdeen, Scotland. His research showed that exposing a developing female sheep fetus to low doses of chemicals in the modern-day environment can disturb the development of the ovary

“Our ‘real life’ model exposed developing sheep fetuses by pasturing their mothers on fields fertilised with either inorganic fertiliser, the control group, or, in the case of the treatment group, with digested human sewage sludge, before and during pregnancy”, said Dr. Fowler.