Researchers at Vanderbilt University Medical Center have discovered a potential way to "tune up" the immune system's ability to kill cancer cells.

In a paper published recently, Eric Sebzda, Ph.D., assistant professor of Pathology, Microbiology and Immunology, graduate student and first author Whitney Rabacal and colleagues describe their discovery in mice of a tolerance mechanism that restrains the activity of natural killer (NK) cells, and a potential way to overcome it.

With an advance that one cryptography expert called a "masterpiece," University of Texas at Austin computer scientists have developed a new method for producing truly random numbers, a breakthrough that could be used to encrypt data, make electronic voting more secure, conduct statistically significant polls and more accurately simulate complex systems such as Earth's climate.

The new method creates truly random numbers with less computational effort than other methods, which could facilitate significantly higher levels of security for everything from consumer credit card transactions to military communications.

Every year, about 350 million hectares of land are devastated by fires worldwide, this corresponds to about the size of India. To estimate the resulting damage to human health and economy, precise prognosis of the future development of fires is of crucial importance. Previous studies often considered climate change to be the most important factor. Now, a group of scientists, including researchers of Karlsruhe Institute of Technology (KIT), has found that population development has the same impact at least. The results are presented in the Nature Climate Change journal (dx.doi.org/10.1038/nclimate2999).

An international team of researchers headed by scientists from the Alfred Wegener Institute has gained new insights into the carbon dioxide exchange between ocean and atmosphere, thus making a significant contribution to solving one of the great scientific mysteries of the ice ages. In the past 800,000 years of climate history, the transitions from interglacials and ice ages were always accompanied by a significant reduction in the carbon dioxide content in the atmosphere. It then fell from 280 to 180 ppm (parts per million). Where this large amount of carbon dioxide went to and the processes through which the greenhouse gas reached the atmosphere again has been controversial until now.

When tiny microbes jam up like fans exiting a baseball stadium, they can do some real damage.

University of California, Berkeley, physicists found this out the hard way when the baker's yeast cells (Saccharomyces cerevisiae) they were studying multiplied so prolifically that they burst the tiny chamber in which they were being raised.

When UC Berkeley postdoctoral fellow Morgan Delarue measured the force the growing mass of cells exerted as they pushed against one another, he calculated that it can be nearly five times higher than the pressure in a car tire -- about 150 psi, or 10 times atmospheric pressure.

Recently, scientists at the Institute of Science and Technology Austria (IST Austria) discovered a new learning rule for a specific type of excitatory synaptic connection in the hippocampus. Their study was now published in the renowned journal Nature Communications on May 13. These synapses are located in the so-called CA3 region of the hippocampus, which plays a critical role for storage and recall of spatial information in the brain. One of its hallmark properties is that memory recall can even be triggered by incomplete cues. This enables the network to complete neuronal activity patterns, a phenomenon termed pattern completion.