BOSTON - (March 31, 2016) - In obesity, the body's immune system can treat tissues as if they are suffering from a low-grade chronic infection. This obesity-induced inflammation is an important contributor to insulin resistance, a condition that can progress into type 2 diabetes. Researchers at Joslin Diabetes Center now have pinpointed a major inflammatory role for "natural killer" (NK) immune cells in abdominal fat--a type of tissue strongly implicated in insulin resistance.

Researchers at the RIKEN Brain Science Institute in Japan have found that a deep-brain structure called the habenula contains two neural circuits that work in a complex interplay to influence whether a fight will be a win or loss.

In humans and other social animals, fighting is an important mode of maintaining a group's social structure. The question of how such aggression is regulated can now be answered, at least for a certain kind of fish, and the key is not brawn, but the brain. Researchers at the RIKEN Brain Science Institute in Japan have found that a deep-brain structure called the habenula contains two neural circuits that work in a complex interplay to influence whether a fight will be a win or loss.

CAMBRIDGE, MA -- MIT biological engineers have created a programming language that allows them to rapidly design complex, DNA-encoded circuits that give new functions to living cells.

Using this language, anyone can write a program for the function they want, such as detecting and responding to certain environmental conditions. They can then generate a DNA sequence that will achieve it.

"It is literally a programming language for bacteria," says Christopher Voigt, an MIT professor of biological engineering. "You use a text-based language, just like you're programming a computer. Then you take that text and you compile it and it turns it into a DNA sequence that you put into the cell, and the circuit runs inside the cell."

A near-atomic level map of Zika virus shows its structure to be largely similar to that of dengue virus and other flaviviruses, but with a notable difference in one key surface protein, report scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The variation in the Zika envelope (E) glycoproteins-- 180 of which are packed on the virus's outer shell-- may provide clues to better understand how Zika virus enters human cells and suggests ways to combat the virus with drugs or vaccines aimed at the newly detailed region.

HOUSTON - (March 31, 2016) - Rice University scientists have determined that two-dimensional boron is a natural low-temperature superconductor. In fact, it may be the only 2-D material with such potential.

Rice theoretical physicist Boris Yakobson and his co-workers published their calculations that show atomically flat boron is metallic and will transmit electrons with no resistance. The work appears this month in the American Chemical Society journal Nano Letters.

The hitch, as with most superconducting materials, is that it loses its resistivity only when very cold, in this case between 10 and 20 kelvins (roughly, minus-430 degrees Fahrenheit). But for making very small superconducting circuits, it might be the only game in town.

NEW YORK, NY (March 31, 2016)--An experimental urine test that detects genetic changes associated with prostate cancer identified 92 percent of men with elevated PSA (prostate-specific antigen) levels who had high-grade cancers, according to a study published today in JAMA Oncology online.