Mutations present in a blood cancer known as follicular lymphoma have revealed new molecular targets for potential treatments, according to researchers at Queen Mary University of London (QMUL) together with collaborators at the Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology.

Follicular lymphoma is a common type of blood cancer and one of the most common non-Hodgkin lymphomas, with more than 2,500 people diagnosed in the UK every year. Whilst the condition is normally responsive to existing therapies, the cancer often returns frequently and eventually develops resistance and, for some, their cancer becomes more aggressive and difficult to treat.

HANOVER, N.H. - Dec. 21, 2015 - We're all familiar with the story of Rudolph the Red-Nosed Reindeer by Robert L. May (a class of 1926 Dartmouth alumnus) but scientifically speaking, what are the optical benefits of a shiny red nose on a foggy Christmas Eve?

1. Sudden cardiac arrest may not be so sudden

Warning signs are common, but are often ignored, in the weeks preceding a heart attack

Abstract: http://www.annals.org/article.aspx?doi=10.7326/M14-2342

URL live when embargo lifts

According to an article published in Annals of Internal Medicine, sudden cardiac arrest may not be an entirely unexpected event. Warning signs are common in the days and weeks leading up to a heart attack, but those symptoms are often ignored. Attention to symptoms and early interventions may improve survival.

Two year olds are adept at using touch screens, and can swipe, unlock, and actively search for features on smartphones and tablets, finds a small study published online in the Archives of Disease in Childhood.

This level of interactivity is akin to play, say the researchers, who suggest that the technology might have a potential role in childhood developmental assessment.

They base their findings on 82 questionnaires on touch screen access and use, completed by the parents of children aged between 12 months and 3 years.

Parents were asked how long their child used touch screens each day, and whether s/he was able to unlock the screen, swipe through pages or images, and recognise and interact with specific features such as app icons for games.

Almost three quarters of the weekend emergency care caseload is linked to excess alcohol intake, finds an activity analysis of one large inner city hospital in England, and published online in Emergency Medicine Journal.

Each case costs between £250 and £850 to treat, or £1 million every year, the analysis shows, indicating substantial costs for urban emergency care departments across the UK faced with similar demand, say the researchers.

The diversity of mammals on Earth exploded straight after the dinosaur extinction event, according to UCL researchers. New analysis of the fossil record shows that placental mammals, the group that today includes nearly 5000 species including humans, became more varied in anatomy during the Paleocene epoch - the 10 million years immediately following the event.