ROCHESTER, Minn. -- Burnout among U.S. physicians is getting worse. An update from a three-year study evaluating burnout and work-life balance shows that American physicians are worse off today than they were three years earlier. These dimensions remained largely unchanged among U.S. workers in general, resulting in a widening gap between physicians and workers in other fields. The study conducted by Mayo Clinic researchers in partnership with the American Medical Association compared data from 2014 to metrics they collected in 2011 and found that now more than half of U.S. physicians are experiencing professional burnout. The findings appear in Mayo Clinic Proceedings.

Scientists have identified a network of nine genes that play a key role in the onset of Alzheimer's Disease.

The finding could help scientists develop new treatments to delay the onset of the disease, said lead researcher Associate Professor Mauricio Arcos-Burgos from The Australian National University (ANU).

In a study of a family of 5,000 people in Columbia, scientists identified genes that delayed the disease, and others that accelerated it, and by how much.

Associate Professor Arcos-Burgos (centre) with Dr Claudio Mastronardi and Dr Hardip Patel. Credit: Stuart Hay, ANU

Folsom, Calif., (Dec. 1, 2015) - A new study published in the Journal of Nutrition found that one serving of walnuts (1oz) may provide 146 calories, which is 39 calories less, or 21 percent fewer, than the 185 calories listed in the USDA Nutrient Database. (1) The study takes into account the digestibility of walnut pieces and halves, and further research is needed to better understand the results of the study and how this technique for calculating calories could potentially affect the calorie count of other foods. The research was led by Dr. David J. Baer, PhD, Supervisory Research Physiologist at the Agricultural Research Service, United States Department of Agriculture (USDA).

Many goals, from finding your dream job to finding a date to the movies, can feel completely out of your control. A common piece of advice to manage this uncertainty is: "Always have a backup plan." But is it actually wise to invest time and energy into backup plans, or is it better to focus all of your energies on trying one way to achieve a goal? To address these questions, psychologists from the University of Zurich developed a new theoretical model to study the use and usefulness of backup plans, which will be published in the January issue of Perspectives on Psychological Science.

Cancer cells are continuously produced in our bodies, where most of them are recognized by our immune systems and destroyed. Some, however, escape this innate surveillance system and find a place to survive and grow.

Several factors expelled by tumor cells are concentrated in the area immediately surrounding the tumor, called the tumor microenvironment. While it is established that these factors support and enhance cancer cell growth and multiplication, it was not known whether these factors influence neighboring normal cells.

In a study into the prevention of HIV transmission, people who took the antiretroviral drug Truvada were 86% less likely to contract the disease than those who took a placebo, report the researchers who led the study.