RamaRao Malla
About RamaRao
Associate Professor, Department of Biochemistry GITAM University. Ph. D., Andhra University, India, 2003
POST DOCTORAL RESEARCH: Department of Cancer Biology and Pharmacology, College of Medicine at Peoria, University of Illnois.
PAPERS PUBLISHED IN NATIONAL AND INTERNATIONAL JOURNALS: 1. Sreelatha Gopinath, Rama Rao Malla, Kiranmai Alapati, Andrew J. Tsung, Jasti S. Rao. "Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression. Carcinogenesis (Under review, 2012) 2. Ganesh Babu Bevara, A.D.Naveen Kumar, D.Bhaskar Rao, K. Laxmi koteswaramma, Swarna pakalapati , Rama Rao Malla. Analysis of antioxidant and anticancer potentials of Urginea indica, an endangered medicinal plant. Journal of plant Biology (Under review, 2012) 3. Kiranmai Alapati, Sreelatha Gopinath, Rama Rao Malla, Venkata Ramesh Dasari, Jasti S. Rao. uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells. Published online on: Thursday, May 24, 2012, Doi: 10.3892/ijo.2012.1496 4. Malla, R.R., Gopinath, S., Gondi, C.S., Alapati, K., Dinh, D.H., Gujrati, M., Rao, J.S. uPAR and Cathepsin B inhibition enhanced radiation –induced apoptosis in Glioma initiating cells. Neuro Oncol. 2012 May 9. 5. Malla, R.R., Gopinath, S., Gondi, C.S., Alapati, K., Dinh, D.H., Gujrati, M., Rao, J.S Knockdown of Cathepsin B and uPAR inhibits CD151 and α3β1 integrin- mediated cell adhesion and invasion in glioma. Molecular carcinogenesis. Molecular carcinogenesis, 2012. Apr 11. doi: 10.1002/mc.21915 6. Malla, R.R., Gopinath, S., Gondi, C.S., Alapati, K., Dinh, D.H., Gujrati, M., Rao, J.S uPAR and CD151 Downregulation Induces Apoptosis by Targeting Calcineurin A to BAD via Bcl-2 in Glioma, J Neurooncol. 2012 Mar;107(1):69-80 7. Malla, R.R., Gopinath, S., Gondi, C.S., Alapati, K., Dinh, D.H., Gujrati, M., Rao, J.S. “Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in gliomas.” Cancer Gene Therapy, 18(6):419, 2011. 8. Gopinath, S., Malla, R.R., Gondi, C.S., Alapati, K., Fassett, D., Klopfenstein, J.D., Dinh, D.H., Gujrati, M., Rao, J.S. Mechanism of p27 Upregulation Induced by Downregulation of Cathepsin B and uPAR in Glioma, Molecular Oncology, 2011 Oct;5(5):426-37. 9. Seema Kumari1*, Chandrasekhar raju Bapala1, M. Ramarao. H2O2 induced radical scavenging activity and DNA strand scission protective activity of extracts from Berberies aristata. Journal of Pharmacy Research, Vol 4, No 2 (2011), 543-545 10. Gopinath, S., Malla, R.R., Gondi, C.S., Alapati, K., Fassett, D., Klopfenstein, J.D., Dinh, D.H., Gujrati, M., Rao, J.S. “Co-depletion of CD151 and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27Kip1 upregulation.” Plos One, 5(7):e11668, 2010. 11. Rao Malla R., Raghu, H., Rao, J.S. “Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells.” Int. J. Oncol., 37:1483-1493, 2010. 12. Malla, R.R., Gopinath, S., Alapati, K., Gondi, C.S., Gujrati, M., Dinh, D.H., Rao, J.S. “Downregulation of uPAR and CD151 induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas.” Plos One, 5(10): e13731, 2010. 13. Raghu, H. Sodadasu, P.K., Malla, R.R., Gondi, C.S., Estes, N., Rao, J.S. “Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells,” BMC Cancer, 10:647, 2010. 14. Seema kumari and Rama Rao Malla. Study on radical scavenging activity and analysis of bioactive compounds in selected Indian medicinal plants. Bioscience, Biotechnology Research Asia, 7(2), 2010. 15. M. Rama Rao, I.Bhaskar Reddy, T. Ramana, S.V.Raja Gopal, B.V. Raman. (2008). A comparative study of antimicrobial activity of Curcuma amada and Alpinia galanga of the Zingiberaceae family. Asian Journal of Chemistry. Vol.20. 16. S.V. Raja Gopal, B.V.Raman, LBhaskar Reddy, M.Rama Rao, Siva Kumar (2008). Antioxidant and free radical scavenging activity of Brown Algae of Visakhapatnam cost. Asian Journal of Chemistry. Vol. 20 (7):5347-5352, 2008. 17. S.V. Raja Gopal, B.V.Raman, LBhaskar Reddy, M.Rama Rao, Siva Kumar (2008).Antimicrobial activity of Lippa citriodora -A folk plant, Journal of pure and applied microbiology. Vol 02 (1), 2008 18. M. Rama Rao¹*, G. Satyanvani², A.D. Naveen Kumar³ And S.V. Raja Gopal¹(2008). Comparative evaluation of the antioxidant potential of selected Indian medicinal plants (Rasayanas). Biomedical & Pharmacology Journal, Vol. 1(2), 375-382. 19. M. Rama Rao*, I.Bhaskar Reddy, S.V.Raja Gopal1, A.D.Naveen Kumar, A.Ramesh And T.Kartika (2008). Effect of Holoptelea Intigrifolia Bark Extract on Radical Scavening And 5’-Lipoxygease Activities. Biomedical & Pharmacology Journal, Vol. 1(2), 349-358. 20. M.Rama Rao, LBhaskar Reddy, S.V.Raja Gopal, B.V.Raman (2007). In vitro inhibition of lipid peroxidation and antimicrobial activity of Sapindus trifoliatus pericarp. Journal of Phytological Research. Vol 20 (2), 215-218. 21. M.Rama Rao, I.Bhaskar Reddy, S.V.Raja Gopal, B.V.Raman, T.Ramana, D.S. Pallavi, D. Hyma.(2007). Radical scavenging and antioxidant activity of ethyl acetate fraction of Plectranthus aromaticus leaves. Biosciences, Biotechnology Research Asia. VolA. N02, 581-588. 22. M.Rama Rao, I.Bhaskar Reddy, S.V.Raja Gopal, B.V.Raman, T. Ramana (2007). Evaluation of antioxidant properties of sweet basil. Asian Journal of Microbiology, Biotechnology & Environmental Science, vol 9, NoA, 811-818. 23. S.V. Raja Gopal, B.V.Raman, I.Bhaskar Reddy, M.Rama Rao, Siva Kumar. (2007). Antioxidants and free radical scavenging activity of Red Algae of Visakhapatnam Coast. Biosciences, Biotechnology Research Asia. VolA. N02, 645-650. 24. D. Bhaskar Rao, P.Subhasghini devi, P. Aparanji, M.Rama Rao and T. Raghava Rao. (2007). In Vitro evaluation of antioxidant properties and their capacity of Alternanthera sessilis and Tephrosia purpurea. Biosciences, Biotechnology Research Asia. Vol 4. N02, 551-560. 25. S.V. Raja Gopa1, Siva Kumar, A. Uma Sankar, M.Rama Rao. (2007). Production and characterization of cellulose by Streptobacillus species-APS-8. Journal of Pure and applied microbiology, Vol. 2, 231-236. 26. M. Rama Rao, I.Bhaskar Reddy and T. Ramana. (2006). Antimicrobial activity of some Indian medicinal plants. Indian Journal of Microbiology Vol 46, No.2, 191-195. 27. I.Bhaskar Reddy, KP.J.Hemalatha, S.V.Raja Gopa1, B.Venkata Raman, M. Rama Rao, D.Siva Prasad and T.G. Reddi. (2006). An eliminative procedure for (3mercaptoethanol interposing in thiol-proteinase assay by Lowry's method. Proc. of AP Akademi of Sciences, Vol 10, No. 3&4: 205. 28. Suryanarayana, P. Vma Sankar, A. Rama Rao, M., Radhakrishnan, T.M. and Ramana, T. (2003). IgE antibody response of Eluesine coracana seed extract in mice. Proc. of AP Akademi of Sciences, Vol. 7. No.4: 261. 29. Ramarao M and Ramana T. (2002). Purification and Properties of Ribonuclease from the leaves of Catharanthus roseus". Proc. of AP Akademi of Sciences, Vol 6, No. 3: 195. PAPERS PRESENTED AT NATIONAL AND INTERNATIONAL CONFERENCES: 1. Ramarao M and Ramana T (1997). Studies on enzyme activities of medicinal plants (abstract). 66th Annual Conference of Society of Biological Chemists (I) held at Visakhapatnam. 2. Ramarao M and Ramana T (1999). Nuclease activities of Vinca rosea (abstract). 68th Annual Conference of Society of Biological Chemists (I) held at Bang lore. 3. Ramarao M and Ramana T (2001). Purification and Properties of Ribonuclease from the leaves of Catharanthus roseus (Oral presentation). National Seminar on Trends in Biotechnology in the 21st century-perspectives in Bioactive Molecules organized by Department of Biotechnology, GITAM, Visakhapatnam. 4. Ramarao M and Ramana T (2002). Studies on medicinal plants. One-day workshop on "Herbal Medicine and its Applications"(UGC Extension programme IX Plan) held at Anakapalle, Andhra Pradesh, India. 5. Dr. M.Rama Rao and Dr.I.Bhaskar Reddy. Presented a paper entitled "In vitro inhibition of lipid peroxidation and antimicrobial activity of Sapindus trifoliatus pericarp" in a National Symposium on "Recent Trends in Biochemistry", organized by Department of Biochemistry, TJPS college, Guntur on December 22, 2006. 6. Ramarao M and Bhaskar Reddy I (2005). Genetically modified bioremediators in a National Seminar on "Advances in the frontiers of Environmental research" held at Department of Environmental Science, Andhra University, Visakhapatnam from November 19-21, 2005. 7. Dr.M.Rama Rao, Dr.I.Bhaskar Reddy. Antimicrobial activity of Sapindus trifoliatus in a National Seminar on "Recent Trends in Microbial Sciences" organized by Departments of Microbiolgy and Biotechnology, JKC College, Guntur on November, 11, 2006. 8. Dr. M.Rama Rao, D.Bhaskar and T. Raghava Rao. "Comparative studies on the evaluation of antioxidants and antioxidant properties of C. ternate and E. prostrata" in 76 Annual Conference of Society of Biological Chemists (I) held at Tirupati on November 23-25, 2007. 9. Dr.M.Rama Rao, Dr.I.Bhaskar Reddy. Antimicrobial activity of Curcuma amada and Alpinia galanga, members of Zingiberaceae family in "National seminar on Biotechnology: Applications in Medicinal Plants & Food Processing" organized by Department of Biological Sciences, Vikram deb autonomous college, Jypore, ORISSA on March 19-20, 2007. 10. Dr. M.Rama Rao, A. D.Naveen Kumar. "Effect of Holoptelea intigrifolia bark extract on radical scavenging and 5'-lipoxygease activities" in International conference on medicinal plants and herbal products held Sri Venkataswera University, Tirupati India on March 7 – 9 , 2008. 11. Dr. M.Rama Rao, D.Bhaskar and T. Raghava Rao. "In Vitro antioxidant properties and their capacity of A. sessiles and T. purpurea" in Indian Science Congress held at Visakhapatnam on January 4-7, 2008 12. Hari Raghu, Prasanna Kumar Sodadasu, Rama Rao Malla, Christopher S.Gondi and Jasti S.Rao. Lipid raft disruption by cholesterol depletion inhibits migration, invasion and angiogenesis by down regulation of uPAR and MM-9 in Breast Carcinoma calls. Proc. Amer. Assoc. Cancer Res., 50: 848 (3516), 2009. 13. Gopinath, S., Malla, R.R., Gondi, C.S., Fassett, D., Klopfenstein, J.D., Dinh, D.H., Gujrati, M., Rao, J.S. “Simultaneous downregulation of uPAR and cathepsin B inhibits angiogenesis and migration and induces caspase 8-mediated apoptosis in U87 stem cells and 4910 glioma xenograft stem cells,” Proc. Amer. Assoc. Cancer Res., 51: 308 (1278), 2010. 14. Gopinath, S., Alapati, K., Malla, R.R., Gondi, C.S., Mohanam, S., Dinh, D.H., Rao, J.S. “Inhibition of PI3K/AKT and MEK/ERK pathways act independently on p27 upregulation induced by downregulation of cathepsin B and uPAR in glioma,” Proc. Amer. Assoc. Cancer Res., 52 (2938),2011. 15. Malla, R.R., Gopinath, S., Alapati, K., Gondi, C.S., Rao, J.S. “Knockdown of cathepsin B and uPAR inhibits CD151 and α3β1 integrin mediated cell adhesion in glioma,” Proc. Amer. Assoc. Cancer Res., 52 (1529), 2011. 16. Ramarao Malla and Jasti S Rao. A novel strategy for the treatment of glioma – siRNA technology, “International conference on Biotehcnology in pharma and food industries, 29th &30th, July 2011. (Invited Talk) 17. Ramarao Malla. Recent highlights on global cancer research, “AP Science Congress”, 14th -16th, Nov, 2011. (Special talk). 18. Seema Kumari and Ramarao Malla. A study on oxidative damage protective activity of bioactive compounds from ethyl acetate fraction of Beriberis aristata. “AP Science Congress”, 14th -16th, Nov, 2011. 19. Ramarao Malla. Invited speaker, BIOMET-2011 on 28th Nov, 2011 at Aditya Degree College, Kakinada 20. Ramarao Malla. Invited speaker, One day State level Conference on 29th January, 2012 at MRPG College, Vizianagaram. 21. Kiranmai Alapati, Venkata Ramesh Dasari, Sreelatha Gopinath, Rama Rao Malla, Meena Gujrati, Jasti S. Rao “uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton and migration of glioma initiating cells,” Proc. Amer. Assoc. Cancer Res., 53 (475), 2012. 22. Sreelatha Gopinath, Rama Rao Malla, Kiranmai Alapati, Andrew J. Tsung, Jasti S. Rao. Cathepsin B and uPAR downregulation sensitizes glioma initiating cells to radiation induced cell cycle arrest. Proc. Amer. Assoc. Cancer Res., 53 (3046), 2012. 23. Ramarao Malla and Jasti S Rao. siRNA technology as a powerful tool to suppress CD133 positive glioma initiating cells. “National Seminar on Present Perspectives of Bioactive Molecules and Biotechnology, organized by Andhra University, 30th & 31st, May 2012 (Invited Talk). 24. Ganesh Babu, A.D. Naveen and Ramarao Malla. Antioxidant and anticancer potentials of white and red varieties of Urgenia indica. “National Seminar on Present Perspectives of Bioactive Molecules and Biotechnology, organized by Andhra University, 30th & 31st, May 2012. 25. A.D. Naveen, Ganesh Babu and Ramarao Malla. In vitro antioxidant and anti-inflammatory activities of stem bark extracts of Semecarpus anacardium. “National Seminar on Present Perspectives of Bioactive Molecules and Biotechnology, organized by Andhra University, 30th & 31st, May 2012.
PAPERS PUBLISHED IN NATIONAL AND INTERNATIONAL JOURNALS: 1. Sreelatha Gopinath, Rama Rao Malla, Kiranmai Alapati, Andrew J. Tsung, Jasti S. Rao. "Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression. Carcinogenesis (Under review, 2012) 2. Ganesh Babu Bevara, A.D.Naveen Kumar, D.Bhaskar Rao, K. Laxmi koteswaramma, Swarna pakalapati , Rama Rao Malla. Analysis of antioxidant and anticancer potentials of Urginea indica, an endangered medicinal plant. Journal of plant Biology (Under review, 2012) 3. Kiranmai Alapati, Sreelatha Gopinath, Rama Rao Malla, Venkata Ramesh Dasari, Jasti S. Rao. uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells. Published online on: Thursday, May 24, 2012, Doi: 10.3892/ijo.2012.1496 4. Malla, R.R., Gopinath, S., Gondi, C.S., Alapati, K., Dinh, D.H., Gujrati, M., Rao, J.S. uPAR and Cathepsin B inhibition enhanced radiation –induced apoptosis in Glioma initiating cells. Neuro Oncol. 2012 May 9. 5. Malla, R.R., Gopinath, S., Gondi, C.S., Alapati, K., Dinh, D.H., Gujrati, M., Rao, J.S Knockdown of Cathepsin B and uPAR inhibits CD151 and α3β1 integrin- mediated cell adhesion and invasion in glioma. Molecular carcinogenesis. Molecular carcinogenesis, 2012. Apr 11. doi: 10.1002/mc.21915 6. Malla, R.R., Gopinath, S., Gondi, C.S., Alapati, K., Dinh, D.H., Gujrati, M., Rao, J.S uPAR and CD151 Downregulation Induces Apoptosis by Targeting Calcineurin A to BAD via Bcl-2 in Glioma, J Neurooncol. 2012 Mar;107(1):69-80 7. Malla, R.R., Gopinath, S., Gondi, C.S., Alapati, K., Dinh, D.H., Gujrati, M., Rao, J.S. “Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in gliomas.” Cancer Gene Therapy, 18(6):419, 2011. 8. Gopinath, S., Malla, R.R., Gondi, C.S., Alapati, K., Fassett, D., Klopfenstein, J.D., Dinh, D.H., Gujrati, M., Rao, J.S. Mechanism of p27 Upregulation Induced by Downregulation of Cathepsin B and uPAR in Glioma, Molecular Oncology, 2011 Oct;5(5):426-37. 9. Seema Kumari1*, Chandrasekhar raju Bapala1, M. Ramarao. H2O2 induced radical scavenging activity and DNA strand scission protective activity of extracts from Berberies aristata. Journal of Pharmacy Research, Vol 4, No 2 (2011), 543-545 10. Gopinath, S., Malla, R.R., Gondi, C.S., Alapati, K., Fassett, D., Klopfenstein, J.D., Dinh, D.H., Gujrati, M., Rao, J.S. “Co-depletion of CD151 and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27Kip1 upregulation.” Plos One, 5(7):e11668, 2010. 11. Rao Malla R., Raghu, H., Rao, J.S. “Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells.” Int. J. Oncol., 37:1483-1493, 2010. 12. Malla, R.R., Gopinath, S., Alapati, K., Gondi, C.S., Gujrati, M., Dinh, D.H., Rao, J.S. “Downregulation of uPAR and CD151 induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas.” Plos One, 5(10): e13731, 2010. 13. Raghu, H. Sodadasu, P.K., Malla, R.R., Gondi, C.S., Estes, N., Rao, J.S. “Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells,” BMC Cancer, 10:647, 2010. 14. Seema kumari and Rama Rao Malla. Study on radical scavenging activity and analysis of bioactive compounds in selected Indian medicinal plants. Bioscience, Biotechnology Research Asia, 7(2), 2010. 15. M. Rama Rao, I.Bhaskar Reddy, T. Ramana, S.V.Raja Gopal, B.V. Raman. (2008). A comparative study of antimicrobial activity of Curcuma amada and Alpinia galanga of the Zingiberaceae family. Asian Journal of Chemistry. Vol.20. 16. S.V. Raja Gopal, B.V.Raman, LBhaskar Reddy, M.Rama Rao, Siva Kumar (2008). Antioxidant and free radical scavenging activity of Brown Algae of Visakhapatnam cost. Asian Journal of Chemistry. Vol. 20 (7):5347-5352, 2008. 17. S.V. Raja Gopal, B.V.Raman, LBhaskar Reddy, M.Rama Rao, Siva Kumar (2008).Antimicrobial activity of Lippa citriodora -A folk plant, Journal of pure and applied microbiology. Vol 02 (1), 2008 18. M. Rama Rao¹*, G. Satyanvani², A.D. Naveen Kumar³ And S.V. Raja Gopal¹(2008). Comparative evaluation of the antioxidant potential of selected Indian medicinal plants (Rasayanas). Biomedical & Pharmacology Journal, Vol. 1(2), 375-382. 19. M. Rama Rao*, I.Bhaskar Reddy, S.V.Raja Gopal1, A.D.Naveen Kumar, A.Ramesh And T.Kartika (2008). Effect of Holoptelea Intigrifolia Bark Extract on Radical Scavening And 5’-Lipoxygease Activities. Biomedical & Pharmacology Journal, Vol. 1(2), 349-358. 20. M.Rama Rao, LBhaskar Reddy, S.V.Raja Gopal, B.V.Raman (2007). In vitro inhibition of lipid peroxidation and antimicrobial activity of Sapindus trifoliatus pericarp. Journal of Phytological Research. Vol 20 (2), 215-218. 21. M.Rama Rao, I.Bhaskar Reddy, S.V.Raja Gopal, B.V.Raman, T.Ramana, D.S. Pallavi, D. Hyma.(2007). Radical scavenging and antioxidant activity of ethyl acetate fraction of Plectranthus aromaticus leaves. Biosciences, Biotechnology Research Asia. VolA. N02, 581-588. 22. M.Rama Rao, I.Bhaskar Reddy, S.V.Raja Gopal, B.V.Raman, T. Ramana (2007). Evaluation of antioxidant properties of sweet basil. Asian Journal of Microbiology, Biotechnology & Environmental Science, vol 9, NoA, 811-818. 23. S.V. Raja Gopal, B.V.Raman, I.Bhaskar Reddy, M.Rama Rao, Siva Kumar. (2007). Antioxidants and free radical scavenging activity of Red Algae of Visakhapatnam Coast. Biosciences, Biotechnology Research Asia. VolA. N02, 645-650. 24. D. Bhaskar Rao, P.Subhasghini devi, P. Aparanji, M.Rama Rao and T. Raghava Rao. (2007). In Vitro evaluation of antioxidant properties and their capacity of Alternanthera sessilis and Tephrosia purpurea. Biosciences, Biotechnology Research Asia. Vol 4. N02, 551-560. 25. S.V. Raja Gopa1, Siva Kumar, A. Uma Sankar, M.Rama Rao. (2007). Production and characterization of cellulose by Streptobacillus species-APS-8. Journal of Pure and applied microbiology, Vol. 2, 231-236. 26. M. Rama Rao, I.Bhaskar Reddy and T. Ramana. (2006). Antimicrobial activity of some Indian medicinal plants. Indian Journal of Microbiology Vol 46, No.2, 191-195. 27. I.Bhaskar Reddy, KP.J.Hemalatha, S.V.Raja Gopa1, B.Venkata Raman, M. Rama Rao, D.Siva Prasad and T.G. Reddi. (2006). An eliminative procedure for (3mercaptoethanol interposing in thiol-proteinase assay by Lowry's method. Proc. of AP Akademi of Sciences, Vol 10, No. 3&4: 205. 28. Suryanarayana, P. Vma Sankar, A. Rama Rao, M., Radhakrishnan, T.M. and Ramana, T. (2003). IgE antibody response of Eluesine coracana seed extract in mice. Proc. of AP Akademi of Sciences, Vol. 7. No.4: 261. 29. Ramarao M and Ramana T. (2002). Purification and Properties of Ribonuclease from the leaves of Catharanthus roseus". Proc. of AP Akademi of Sciences, Vol 6, No. 3: 195. PAPERS PRESENTED AT NATIONAL AND INTERNATIONAL CONFERENCES: 1. Ramarao M and Ramana T (1997). Studies on enzyme activities of medicinal plants (abstract). 66th Annual Conference of Society of Biological Chemists (I) held at Visakhapatnam. 2. Ramarao M and Ramana T (1999). Nuclease activities of Vinca rosea (abstract). 68th Annual Conference of Society of Biological Chemists (I) held at Bang lore. 3. Ramarao M and Ramana T (2001). Purification and Properties of Ribonuclease from the leaves of Catharanthus roseus (Oral presentation). National Seminar on Trends in Biotechnology in the 21st century-perspectives in Bioactive Molecules organized by Department of Biotechnology, GITAM, Visakhapatnam. 4. Ramarao M and Ramana T (2002). Studies on medicinal plants. One-day workshop on "Herbal Medicine and its Applications"(UGC Extension programme IX Plan) held at Anakapalle, Andhra Pradesh, India. 5. Dr. M.Rama Rao and Dr.I.Bhaskar Reddy. Presented a paper entitled "In vitro inhibition of lipid peroxidation and antimicrobial activity of Sapindus trifoliatus pericarp" in a National Symposium on "Recent Trends in Biochemistry", organized by Department of Biochemistry, TJPS college, Guntur on December 22, 2006. 6. Ramarao M and Bhaskar Reddy I (2005). Genetically modified bioremediators in a National Seminar on "Advances in the frontiers of Environmental research" held at Department of Environmental Science, Andhra University, Visakhapatnam from November 19-21, 2005. 7. Dr.M.Rama Rao, Dr.I.Bhaskar Reddy. Antimicrobial activity of Sapindus trifoliatus in a National Seminar on "Recent Trends in Microbial Sciences" organized by Departments of Microbiolgy and Biotechnology, JKC College, Guntur on November, 11, 2006. 8. Dr. M.Rama Rao, D.Bhaskar and T. Raghava Rao. "Comparative studies on the evaluation of antioxidants and antioxidant properties of C. ternate and E. prostrata" in 76 Annual Conference of Society of Biological Chemists (I) held at Tirupati on November 23-25, 2007. 9. Dr.M.Rama Rao, Dr.I.Bhaskar Reddy. Antimicrobial activity of Curcuma amada and Alpinia galanga, members of Zingiberaceae family in "National seminar on Biotechnology: Applications in Medicinal Plants & Food Processing" organized by Department of Biological Sciences, Vikram deb autonomous college, Jypore, ORISSA on March 19-20, 2007. 10. Dr. M.Rama Rao, A. D.Naveen Kumar. "Effect of Holoptelea intigrifolia bark extract on radical scavenging and 5'-lipoxygease activities" in International conference on medicinal plants and herbal products held Sri Venkataswera University, Tirupati India on March 7 – 9 , 2008. 11. Dr. M.Rama Rao, D.Bhaskar and T. Raghava Rao. "In Vitro antioxidant properties and their capacity of A. sessiles and T. purpurea" in Indian Science Congress held at Visakhapatnam on January 4-7, 2008 12. Hari Raghu, Prasanna Kumar Sodadasu, Rama Rao Malla, Christopher S.Gondi and Jasti S.Rao. Lipid raft disruption by cholesterol depletion inhibits migration, invasion and angiogenesis by down regulation of uPAR and MM-9 in Breast Carcinoma calls. Proc. Amer. Assoc. Cancer Res., 50: 848 (3516), 2009. 13. Gopinath, S., Malla, R.R., Gondi, C.S., Fassett, D., Klopfenstein, J.D., Dinh, D.H., Gujrati, M., Rao, J.S. “Simultaneous downregulation of uPAR and cathepsin B inhibits angiogenesis and migration and induces caspase 8-mediated apoptosis in U87 stem cells and 4910 glioma xenograft stem cells,” Proc. Amer. Assoc. Cancer Res., 51: 308 (1278), 2010. 14. Gopinath, S., Alapati, K., Malla, R.R., Gondi, C.S., Mohanam, S., Dinh, D.H., Rao, J.S. “Inhibition of PI3K/AKT and MEK/ERK pathways act independently on p27 upregulation induced by downregulation of cathepsin B and uPAR in glioma,” Proc. Amer. Assoc. Cancer Res., 52 (2938),2011. 15. Malla, R.R., Gopinath, S., Alapati, K., Gondi, C.S., Rao, J.S. “Knockdown of cathepsin B and uPAR inhibits CD151 and α3β1 integrin mediated cell adhesion in glioma,” Proc. Amer. Assoc. Cancer Res., 52 (1529), 2011. 16. Ramarao Malla and Jasti S Rao. A novel strategy for the treatment of glioma – siRNA technology, “International conference on Biotehcnology in pharma and food industries, 29th &30th, July 2011. (Invited Talk) 17. Ramarao Malla. Recent highlights on global cancer research, “AP Science Congress”, 14th -16th, Nov, 2011. (Special talk). 18. Seema Kumari and Ramarao Malla. A study on oxidative damage protective activity of bioactive compounds from ethyl acetate fraction of Beriberis aristata. “AP Science Congress”, 14th -16th, Nov, 2011. 19. Ramarao Malla. Invited speaker, BIOMET-2011 on 28th Nov, 2011 at Aditya Degree College, Kakinada 20. Ramarao Malla. Invited speaker, One day State level Conference on 29th January, 2012 at MRPG College, Vizianagaram. 21. Kiranmai Alapati, Venkata Ramesh Dasari, Sreelatha Gopinath, Rama Rao Malla, Meena Gujrati, Jasti S. Rao “uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton and migration of glioma initiating cells,” Proc. Amer. Assoc. Cancer Res., 53 (475), 2012. 22. Sreelatha Gopinath, Rama Rao Malla, Kiranmai Alapati, Andrew J. Tsung, Jasti S. Rao. Cathepsin B and uPAR downregulation sensitizes glioma initiating cells to radiation induced cell cycle arrest. Proc. Amer. Assoc. Cancer Res., 53 (3046), 2012. 23. Ramarao Malla and Jasti S Rao. siRNA technology as a powerful tool to suppress CD133 positive glioma initiating cells. “National Seminar on Present Perspectives of Bioactive Molecules and Biotechnology, organized by Andhra University, 30th & 31st, May 2012 (Invited Talk). 24. Ganesh Babu, A.D. Naveen and Ramarao Malla. Antioxidant and anticancer potentials of white and red varieties of Urgenia indica. “National Seminar on Present Perspectives of Bioactive Molecules and Biotechnology, organized by Andhra University, 30th & 31st, May 2012. 25. A.D. Naveen, Ganesh Babu and Ramarao Malla. In vitro antioxidant and anti-inflammatory activities of stem bark extracts of Semecarpus anacardium. “National Seminar on Present Perspectives of Bioactive Molecules and Biotechnology, organized by Andhra University, 30th & 31st, May 2012.
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