Rational use of medicines remains to be one of the most challenging problems in health systems worldwide. Kazan Federal University researchers conducted a practical study to assess the impact of introducing evidence-based principles to the practice of medicine procurement in order to manage budget expenditures on medicines of a multidisciplinary health facility for the period of 2011-2014.

This case-study suggests that a genetic predisposition, such as susceptibility to sunburn, can result in abnormal growth or “tumour” formation without proper sunscreen protection, as previously described in Science 2.0 [Sunburn with Sunscreen: A Case-Study - April 20, 2011].

Researchers long have known that some portion of the risk of developing cancer is hereditary and that inherited genetic errors are very important in some tumors but much less so in others.

In a new analysis, researchers have shed light on these hereditary elements across 12 cancer types -- showing a surprising inherited component to stomach cancer and providing some needed clarity on the consequences of certain types of mutations in well-known breast cancer susceptibility genes, BRCA1 and BRCA2.

The study, from Washington University School of Medicine in St. Louis, appears Dec. 22 in the journal Nature Communications.

Borrowing insights from techniques used to image cancer, Stanford scientists have devised a new method for generating "training images" that can be used to fine-tune models of uncertainty about underground physical processes and structures.

Having an accurate picture of the planet's subsurface is crucial for rational decision-making across a wide variety of activities, including environmental cleanup, oil and natural gas well-drilling, and the underground sequestration of greenhouse gases that contribute to climate change.

Christmas has become a cultural event, associated with the giving of gifts and lavish meals with friends and family.

But the traditional understanding of Christmas is that it’s a Christian celebration of the birth of Jesus.

The idea of giving gifts may be traced to the Bible, in which the infant Jesus was presented with gold, frankincense and myrrh by the Three Wise Men, named in apocryphal texts as Caspar, Balthasar and Melchior.

This received a boost in the Middle Ages, when Boxing Day, December 26, became a holiday when masters gave their apprentices and other employees “boxes” – that is, gifts.

Astrophysicists have obtained precise measurements for an object orbiting a black hole five billion light years away - and the innermost region of a disc of matter in orbital motion around a supermassive black hole tucked inside the quasar known as Einstein’s Cross (Q2237-0305).

This constitutes the most precise set of measurements achieved to date for such a small and distant object, and was made possible thanks to years of monitoring as part of the OGLE and GLITP gravitational microlensing projects, which have had their lenses trained on this quasar for 12 and 9 years, respectively. Typically, astronomers can only detect bright objects that emit a lot of light or large objects that block background light.

America is the fattest country on Earth and there are efforts being made to insure the 100 thin women still remaining don't set a bad example by not being obese. S. Bryn Austin, director of the Harvard Chan School's Strategic Training Initiative for the Prevention of Eating Disorders (STRIPED) and Director of the Sexual Orientation and Gender Identity and Expression working group is leading the call to prohibit thin fashion models from participating in fashion shows or photo shoots if they are too thin.

TORONTO, Dec. 17, 2015 - More than one in nine people with hepatitis C in Canada spend time in a correctional facility each year and researchers said this presents a unique opportunity to focus hepatitis C prevention and control efforts in incarcerated populations.

People who have spent time in correctional facilities have higher risk factors for hepatitis C, including injection drug use and needle sharing, both in custody and in the community, according to the paper published online today in the Canadian Journal of Public Health.

Climate change is rapidly heating up lakes around the world, threatening freshwater supplies and ecosystems across the planet, according to a study spanning six continents.

More than 60 scientists took part in the research, published in the journal Geophysical Research Letters and announced today at the fall meeting of the American Geophysical Union.

AMES, IA - As the popularity of fresh culinary herbs increases, growers are looking to year-round production methods to supply distributors and local consumers. In colder climates, culinary herb growers rely on controlled indoor environments and often employ hydroponic production techniques. A new study of basil varieties grown using two popular techniques found that plant performance is more likely related to the choice of cultivar than the type of hydroponic system used.