Sometimes, science means staying awake for two days straight.

But losing sleep is a small sacrifice to make, if you want to learn more about tiny bacteria that sicken half a million Americans each year, kill more than 14,000 of them, and rack up $4.8 billion in health care costs.

That's what drove a team of University of Michigan scientists to work around the clock to study the bacterium called Clostridium difficile, or C. difficile, the bane of hospitals and nursing homes. Most patients develop it after taking antibiotics.

Statins, cholesterol-lowering drugs prescribed to prevent heart attacks for the last two decades, are not as effective nor as safe as claimed, according to a review by Dr. David M. Diamond, a psychologist at the University of South Florida, and Dr. Uffe Ravnskov, an independent researcher.

According to Diamond and Ravnskov, statins produce a dramatic reduction in cholesterol levels, but they have "failed to substantially improve cardiovascular outcomes." They further state that the many studies touting the efficacy of statins have not accounted for the adverse side effects of the drugs, but supporters of statins have used what the authors refer to as "statistical deception" to make inflated claims about their effectiveness. 

Electrical impulses play an important role in cells of the human body. For example, neurons use these impulses to transmit information along their branches and the body also uses them to control the contraction of muscles. The impulses are generated when special channel proteins open in the outer envelope of the cells, allowing charged molecules (ions) to enter or exit the cell. These proteins are referred to as ion channels.

Women who understand the risk of over-detection and over-diagnosis associated with mammography screening have lower intentions to have a breast screening test, according to a new study. Over-detection and over-diagnosis refers to the diagnosis and treatment of breast cancer that would not have presented clinically during a woman's lifetime.

Such a diagnosis, and the resulting overtreatment, can harm women physically and emotionally.

A new family of bacteria that are common in malaria mosquitoes has been described by researchers at Swedish University of Agricultural Sciences (SLU) and Uppsala University in Sweden, Justus-Liebig-Universität Giessen, Germany, and the Veterinärmedizinische Universität, Austria. Now, attempts are made to use these bacteria in the fight against malaria.

Ovarian cancer is the deadliest of all cancers affecting the female reproductive system with very few effective treatments available. Prognosis is even worse among patients with certain subtypes of the disease. Now, researchers at The Wistar Institute have identified a new therapeutic target in a particularly aggressive form of ovarian cancer, paving the way for what could be the first effective targeted therapy of its kind for the disease.

The findings were published online by the journal Nature Medicine.

Frequent menopausal vasomotor symptoms (VMS), including hot flashes and night sweats, lasted for more than seven years during the transition to menopause for more than half of the women in a large study and African American women reported the longest total VMS duration, according to a new study.

VMS are the hallmark of the menopausal transition and they can affect the quality of women's lives. Up to 80 percent of women experience VMS during the transition to menopause and, despite the pervasiveness of these symptoms, robust estimates about how long VMS last are lacking.

It's Academy Awards time, which means the science community is aflame with debates about whether Hollywood elites are racist, sexist, bigoted or not liberal enough...okay, no one in science actually debates any of that the way Hollywood does, but we do get to think about how science did in film in 2014.

Science is big in culture these days - everyone loves it. You can't watch a blurb about a superhero movie where a character jumps out of a building and into a helicopter because the helicopter turns on its side without someone making the movie claiming they are grounded in science. 

Picture this: For the past two weeks you have felt continuously dejected. You have lost interest in what normally makes you happy. Perhaps you’ve slept poorly or lost your appetite. There is a risk that you have one of the most common maladies in the world: Depression.

You decide to see a doctor. She considers different treatments and finally she gives you a prescription for a small box of antidepressants. Whether they will help you is unclear. Some patients report an effect after two or three weeks, others don’t notice any change at all. Some even get even more depressed.

More depressed? If it is actually a healthy person who doesn't have clinical depression, it's certainly possible. 

Measurements at BESSY II have shown how spin filters forming within magnetic sandwiches influence tunnel magnetoresistance - results that can help in designing spintronic components. In doing so, the teams enhanced our understanding of processes that are important for future TMR data storage devices and other spintronic components.