Patients taking anti-obesity drugs will only see “modest” weight loss and many will remain significantly obese or overweight, according to a study published in the British Medical Journal.
The study, which looked at the long-term effectiveness of anti-obesity medications, found that three drugs recommended for long-term use - orlistat, sibutramine and rimonabant, reduced weight by less than 11 pounds (5 kg). This equated to a loss of less than 5% of total body weight. Guidelines from the National Institute for Clinical Excellence recommend stopping the use of anti-obesity drugs if 5% of total body weight is not lost after three months.
While making changes to lifestyle and diet are recommended as the initial treatment for obesity, the use of anti-obesity drugs is common.