A study in Proceedings of the National Academy of Sciences says that metformin, the world's most widely used anti-diabetic drug, slows aging and increases lifespan.
In their experiments, the researchers tease out the mechanism behind metformin's age-slowing effects: the drug causes an increase in the number of toxic oxygen molecules released in the cell and this, surprisingly, increases cell robustness and longevity in the long term.
Mitochondria – the energy factories in cells – generate tiny electric currents to provide the body's cells with energy. Highly reactive oxygen molecules are produced as a by-product of this process.