Patients who increased doses of opioid medicines to manage chronic pain were more likely to experience an increase in depression, according a new paper in Pain which expands findings in a previous study of Veterans Administration (VA) patients.
Jeffrey Scherrer, Ph.D., associate professor for family and community medicine at Saint Louis University, and his colleagues studied questionnaires from 355 patients from nine practices in the Residency Research Network of Texas who reported chronic low back pain initially and at one-year and two-year follow ups. The respondents to the survey were 72.4 percent female, older than 46 (75.2 percent) and mostly of Hispanic or African-American descent (57.5 percent).