A team of scientists at JILA, a joint institute of the National Institute of Standards and Technology (NIST) and the University of Colorado (CU) at Boulder, has shown that by sampling a person’s breath with laser light they can detect molecules in the breath that may be markers for diseases like asthma or cancer. While many studies have been done to showcase the potential of optical technologies for breath analysis, the JILA approach takes an important step toward demonstrating the full power of optics for this prospective medical application.
The technique, called cavity-enhanced direct optical frequency comb spectroscopy, may one day allow doctors to screen people for certain diseases simply by sampling their breath. “This technique can give a broad picture of many different molecules in the breath all at once,” says Jun Ye, who led the research. He is a fellow of JILA, a fellow of NIST and a professor adjoint at CU-Boulder’s Department of Physics.