Contrary to some reports, the epilepsy drug oxcarbazepine does not appear to prevent migraine, according to research published in the February 12, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology.
The nearly five-month study involved 170 men and women at clinics across the United States with half of the group receiving a daily dose of oxcarbazepine; the other half took placebo. Both groups included people who had three to nine migraine attacks within a month.
Researchers found no difference between the oxcarbazepine and placebo groups in the change in the number of migraine attacks from the beginning to the end of the study.