Enzymes are biological catalysts that are made from a string of amino acids, which fold into specific three-dimensional protein structures. Without them, life would not exist. They are a valuable model for understanding the intricate works of nature. These molecular machines are responsible for initiating chemical reactions within the body. Millions of years of natural selection have fine-tuned the activity of such enzymes, allowing chemical reactions to take place millions of times faster.
In order to create artificial enzymes, a comprehensive understanding of the structure of natural enzymes, their mode of action, as well as advanced protein engineering techniques is needed. A team of scientists from the University of Washington, Seattle, and the Weizmann Institute of Science, Israel, made a crucial breakthrough toward this endeavor.
They have succeeded in creating a new type of enzyme for a reaction for which no naturally occurring enzyme has evolved.