Sitting for hours at your desk is bad for you, even fatal in the long run. Paul Knoepfler has recently again made me aware of this – read his Thinking on your feet: practical suggestions for creating and using a standing workstation. There is no point in writing yet another article, because you will have forgotten everything about it after five minutes. So, this here will be different.

Chemistry space refers to the combinatorial and configurational space spanned by all possible molecules (i.e. those combination of atoms allowed by the rules of valence in energetically stable spatial arrangements). It is estimated that the total number of possible small organic molecules populating chemistry space could exceed 10⁶⁰ — a number that exceeds the total number of atoms in the known universe, and is vastly greater than the number of molecules that have actually been isolated or synthesized.

A new study, published in Science, describes a multi-gene synthetic circuit that can distinguish between cancer and non-cancer cells, after which it can target the cancer cells for destruction. Through recognizing five intracellular cancer-specific molecules, the circuit is able to accurately identify cancer cells, which, after detection, are destroyed.

Finding the right combination of molecules was challenging. Looking among microRNA molecules, which are post-transcriptional regulators, the researchers were eventually able to find one miRNA combination that was typical for HeLa, or cervical cancer, cells. The combination is made up out of five specific miRNAs, and is sufficient to identify HeLA cells among healthy cells (see figure 1).

Bias in science academia is a big topic, but it's selective.  If there are fewer women, it is regarded as a hostile environment but if there are no Republicans that is their choice.  

Penn State researchers have added something new into the mix - hormones.  If you are a woman who wanted to be a physicist, you may have been fighting your own sex hormones to do it, they say.  They did it by looking at people's interest in occupations that exhibit sex differences in the general population and are relevant to science, technology, engineering and mathematics (STEM) careers.