17 genomes of supercentenarians, people living beyond 110 years of age, haven't led us any closer to discovering protein-altering variants significantly associated with extreme longevity, according to a study in PLOS ONE by Hinco Gierman from Stanford University and colleagues.

There are 74 supercentenarians alive worldwide, with 22 in the United States. The authors of this study performed whole-genome sequencing on 17 of them to explore the genetic basis underlying extreme human longevity. 

If surveys are accurate, up to 20 percent of students have taken Modafinil (Provigil), a psychostimulant embraced by "lifehackers" in the naturalistic crowd, to boost their ability to study and improve their chances of exam success. 

It is claimed, mostly by other students and readers of New York Magazine, that Modafinil is a 'smart' drug. Yet that isn't the case. Just like people without celiac disease are actually damaging their health giving up gluten and replacing it with the extra sugar, extra fat, hydroxypropyl methyl cellulose and xanthan gum found in gluten-free foods, healthy students who take Modafinil instead find their performance impaired by the drug. 

In hydraulic fracturing - fracking - a mixture of sand, water and chemicals is injected into deep wells to release fossil fuels. This has led to environmental corporation claims that the reduced emissions from natural gas are being offset environmentally by surfactants.

A surfactant is basically a detergent. It reduces the surface tension between water and oil, allowing for more oil to be extracted from porous rock underground. 

 A University of Colorado Boulder study has found there is little to fear. The surfactant chemicals found in samples of fracking fluid collected in five states were no more toxic than substances commonly found in homes - including organic products.

Can homeopathy actually work if someone knows it is a placebo? What if, for example, a skeptical Science 2.0 group was told they got a placebo and that nutritionists were getting medicine? Would we feel better anyway?(1)

Of course it's possible, it just wouldn't be due to magic water. It's a mystery of biology why some people just feel better taking something. That is why homeopathy still exists a few hundred years after its invention even though it has never worked.(2)

Does the placebo effect apply to dogs? Do they understand the concept of medicine? If not, they have a placebo effect.

In the last 30 years, the United States has grown more food using less land and with less environmental strain than ever believed possible. Fertilizers are better, pesticides are better and genetic modification has led to less need for both.

But some scientifically developing nations, including much of Europe, are still using more antiquated approaches, and then means a lot of nitrogen. Nitrogen boosts plant growth and yield even on poor soils, which helps plants avoid the typical characteristics of nitrogen deficiency - stunted growth and pale or yellow leaves - but in environmentally intensive approaches like organic farming, the left over nitrogen can be substantial. 

Hey, does anyone want this comet?

For the first time, mankind has successfully landed on a comet - a journey over 10 years in the making.

After a seven-hour final descent, Rosetta’s Philae probe signaled from the surface of Comet 67P/Churyumov–Gerasimenko and the message arrived on Earth at 16:03 GMT, completing the longest part of a 4 billion mile journey through the solar system.

The landing site, named Agilkia and located on the head of the bizarre double-lobed object, was chosen based on images and data collected at distances of 30–100 km from the comet. Those first images soon revealed the comet as a world littered with boulders, towering cliffs and daunting precipices and pits, with jets of gas and dust streaming from the surface.

The Six Billion Dollar Man is getting a little bit closer, not just to movie theaters, but in real life. 

A new development toward a prosthetic retina could help counter conditions that result from retinal degeneration, a life-altering health issue for many people, especially as they age.

Trans fats are bad, they damage metabolic health in kids, according to experts and policy makers. So they were banned. Happy Meals too. And drinks with sugar.

It's fashionable in nutritional circles to demonize sodas but they also embrace a lot of unsubstantiated food fads. How much real prospective fact-finding has gone into their beliefs?
Not much, it is instead epidemiology putting two curves next to each other and declaring causation. 

FK506 binding protein 51 (FKBP51) is an Hsp90 co-chaperone and regulator of the glucocorticoid receptor, and consequently of stress physiology. It regulates acute and chronic effects of treatment with antidepressants via autophagic pathways (processes by which cells break down and recycle their components) in mice and is linked to the clinical response to antidepressants in humans, according to a new paper. 

Did you spend those pre-school years telling your child how smart and wonderful they are? School is going to be an unwelcome dose of reality.

 While we all want kids to be self-confident, unrealistic perceptions of academic abilities can be harmful, a new study of eighth-graders finds. The more one student feels unrealistically superior to another, the less the two students like each other.