In anticipation of the ISMB BoF session on Open Notebook Science (ONS),I’m trying to come up to speed on ONS discourse. In between ISMBsessions, I’ve started consolidating snippets of blogposts and articles discussing ONS into a single document (in the open here).

As any child knows, to answer the question “how many,” one must start by adding up individual objects in a group. This cognitive ability is shared by animals as diverse as humans and birds. Surprisingly, the exact brain mechanisms responsible for this process remained unknown until now.

Jamie Roitman, Elizabeth Brannon, and Michael Platt from the University of Illinois at Chicago report novel evidence for the existence of “accumulator neurons,” which respond to increasing numbers of items in a display with progressively increasing activity, in the parietal cortex of monkeys.

Colloidal silver is peddled as a cold medicine, decongestant, all-around germ fighter, and a kind of cure-all. Is there any legitimate reason for taking the dietary supplement? The short answer is no, and there may be some serious and strange side effects, reports the August 2007 issue of the Harvard Health Letter.

Silver has several uses in conventional medicine. Silver sulfadiazine is used to treat serious burns. Fabric impregnated with silver is sometimes used as a dressing for wounds or skin infections. And silver nitrate is occasionally used to treat warts and corns.

But there’s no proof that taking colloidal silver by mouth has any benefits.

Michael Hofreiter from the Max Planck Institute for Evolutionary Anthropology in Germany, and colleagues from Switzerland and the United States, announce the sequencing of the complete mitochondrial genome of the mastodon (Mammut americanum), a recently extinct relative of the living elephants that diverged about 26 million years ago.

The sequence was obtained from a tooth dated to 50,000–130,000 years ago, increasing the specimen age for which such palaeogenomic analyses have been done by almost a complete glacial cycle.

Scientists at the University of Sheffield, collaborating with colleagues at the Universities of Portsmouth and Reading, have taken a step back in time and provided a new insight into the lifestyle of a prehistoric flying reptile.

Using new physical and mathematical modelling, Dr Stuart Humphries from the University of Sheffield, along with scientists from the Universities of Portsmouth and Reading, has shown that suggestions that extinct pterosaurs gathered their food by ‘skimming’ the surface of the ocean with their beaks are inaccurate.

A limpet no bigger than a coin could reveal the possible fate of cold-blooded Antarctic marine animals according to new research.

Compared to their temperate and tropical cousins, cold-blooded polar marine animals are incapable of fast growth. Until now scientists assumed that a lack of food in winter was the major limiting factor. Studies of the protein-making abilities of limpets in both the sea around the British Antarctic Survey’s (BAS) Rothera Research Station and in the laboratory aquarium reveal that these animals cannot make proteins – the building blocks of growth - efficiently.

Lead author Dr Keiron Fraser from BAS says,“This is an important step forward in our understanding of the complex biodiversity of Antarctica’s unique ecosystem.

The scientist involved in helping re-introduce the Great Bustard to the UK is “delighted” that birds released at a secret Wiltshire location have laid their first eggs.

Dr Tamas Szekely from the University of Bath says that the announcement from the Great Bustard Group comes a year earlier than predicted, and shows that the project is making good progress.

The Great Bustard is the world’s largest flying bird and although it was hunted as a trophy until it became extinct in the UK in the 1830s, it still lives in stable populations in eastern Europe.

There is little disagreement that the body’s maintenance and repair systems deteriorate with age, even as there is plenty of disagreement as to why.

Stem cells combat the aging process by replenishing old or damaged cells—particularly in the skin, gut, and blood—with a fresh supply to maintain and repair tissue. Unfortunately, new evidence published in the open-access journal PLoS Biology suggests that this regenerative capacity also declines with age as stem cells acquire functional defects.

People who spent more time in the sun as children may have a lower risk of developing multiple sclerosis (MS) than people who had less sun exposure during childhood, according to a study published in the July 24, 2007, issue of Neurology®.

For the study, researchers surveyed 79 pairs of identical twins with the same genetic risk for MS in which only one twin had MS. The twins were asked to specify whether they or their twin spent more time outdoors during hot days, cold days, and summer, and which one spent more time sun tanning, going to the beach and playing team sports as a child.

Drinking more than one soft drink daily — whether it’s regular or diet — may be associated with an increase in the risk factors for heart disease.

“We were struck by the fact that it didn’t matter whether it was a diet or regular soda that participants consumed, the association with increased risk was present,” said Ramachandran Vasan, M.D., senior author of the Framingham Heart Study and professor of medicine at Boston University School of Medicine.