Scientists at the Salk Institute for Biological Studies have identified an enzyme that pumps up a cell’s ability to maintain healthy muscle and restores normal muscle function in genetically engineered mice with weak muscles. The study, published online in Nature Medicine, is the first to explore the part this enzyme plays in a cascade of events triggered by exercise-induced hormones and other signals.

After completing a two-year pilot phase, scientists at the Woods Hole Research Center are expanding the scope of the "National Biomass and Carbon Dataset" for the year 2000 (NBCD2000), the first ever inventory of its kind, by moving into the production phase.


To date, 5 of the 66 mapping zones have been completed in the NBCD2000 project. The remaining 61 will be completed at an approximate rate of one every seven working days. Credit: Wayne Walker/Greg Fiske. Woods Hole Research Center.

Want to know if the International Space Station is over you right now? You can view the location of ESA's Earth-orbiting spacecraft and other ESA-related missions in real-time via a new tracking site.


Credits: ESA

Research shows that adolescents who engage in one form of risky behavior, like drug or alcohol use, are likely to engage in other risky behaviors like self-harm, or having unprotected sex, but often times these behaviors are not discussed during a medical or mental health exam. Now, a new study shows that a simple and brief screening measure called the adolescent risk inventory (ARI) can quickly identify the broad range of risk behaviors found among adolescents.

Recent data from the Lung Allograft Rejection Gene expression Observational (LARGO) study provides compelling evidence that profiling gene expression in peripheral blood can detect organ rejection in lung transplant patients.

Data from the study shows that the immune responses of lung transplant recipients can result in novel molecular signatures identifying the absence or presence of acute cellular rejection (ACR). That molecular signature can be identified using the quantitative real-time polymerase chain reaction (RT-PCR), a technology that measures the intracellular RNA levels of individual genes.

Fish oil, it's been touted as an answer to Alzheimers, arthritis and even weight-loss but now a Queensland University of Technology researcher will test its health benefits in people with chronic kidney disease.

Dietitian Rachel Zabel, from QUT's Institute of Health and Biomedical Innovation in Brisbane, Australia, will investigate the effects of fish oil on patients with kidney disease undergoing dialysis.

A recent describes a new agent, called "Zorro-LNA," which has the potential to stop genetic disorders in their tracks. In the study, researchers from the Karolinska Institute in Stockholm, Sweden, describe how they developed Zorro-LNA to bind with both strands of a gene’s DNA simultaneously, effectively disabling that gene.

This development has clinical implications for virtually every human condition caused by or worsened by dominant defective genes. Examples include: Huntington’s disease, familial high cholesterol, polycystic kidney disease, some instances of glaucoma and colorectal cancer, and neurofibromatosis, among others.

The heart is one of the most energy demanding organs of the human body. Its failure to function properly accounts for 600,000 deaths each year. Similarly, the rainbow trout, native to the Pacific Northwest and beloved as a sport- and food fish, requires dynamic and sustained cardiac function to maintain its health and swimming activity.

Among flagship species for conservation, Lonesome George is perhaps the most renowned. Long thought to be the sole survivor of a species of giant Galápagos tortoise (Geochelone abingdoni), this conservation icon may not be alone for much longer. Researchers headed by investigators at Yale University report these findings in work published online on April 30th in the journal Current Biology.

What a person says is not necessarily an indication of what that person knows because speech is motivated by social circumstances and the desire to influence the listener. Two researchers at the University of Missouri-Columbia have applied this principle to local environmental knowledge by indigenous peoples and are urging other scientists to incorporate more observation and skepticism into their studies.