Matthew Miller, M.D., Sc.D., of the Harvard School of Public Health, Boston, and colleagues, writing in JAMA (doi:10.1001/jamainternmed.2014.1053) analyzed data from 162,625 people (between the ages of 10 to 64 years) with depression who started antidepressant treatment with a selective serotonin reuptake inhibitor at modal (the most prescribed doses on average) or at higher than modal doses from 1998 through 2010. 

Americans are caught in a contradictory cultural schism. If a girl is thin, parents feel like they need to have an intervention. But we are in a war on obese people and politicians are responding to that by banning everything that looks like it can pass the legislature. Pressure to be thin may be making girls fat - except in Europe, where impossibly attractive naked women are on public billboards.

Are Americans so fat because of too much pressure to be thin?

The idea of a smart home sounds promising enough, and a house full of automated gadgets, from light switches to appliances to heating systems, will impress your friends.

Water testing can  be a cumbersome process, with labs and delays and waiting. 

Chemical engineers from McMaster University have reduced the sophisticated chemistry required for testing water safety to a simple pill, by adapting technology found in...a breath strip. 

Want to know if a well is contaminated? Drop a pill in a vial of water and shake it. If the color changes, there's the answer. The development has the potential to dramatically boost access to quick and affordable testing around the world.

The idea occurred to team member Sana Jahanshahi-Anbuhi, a PhD student in Chemical Engineering who came across the breath strips while shopping and realized the same material used in the dissolving strips could have broader applications. 

Who had the privilege to spend eternal life next to the pharaoh?

Kids and other family members, much like today. If you can afford a tomb, that is.

In the Egyptian Valley of the Kings, excavations by Egyptologists from the University of Basel have been working on tomb KV 40, close to the city of Luxor, for three years. From the outside, only a depression in the ground indicated the presence of a subterranean tomb. Up to now, nothing was known about the layout of tomb KV 40 nor for whom it was build and who was buried there.  

If a person commits a violent criminal act, there is a higher chance that a younger sibling will follow in their footsteps than an older one, according to a new paper.

It's been common sense for centuries that violent criminal behavior runs strongly in families but why is unclear. Blame is attributed to shared environmental factors such as poverty, divorce and poor parental supervision. 
This 'social transmission' of violent behaviors suggests that environmental factors within families can be important when it comes to delinquent behavior. 

Should food that has been genetically optimized have a special label attached to it by law?

Advocates say 'yes', it is about awareness, though actual implementations and efforts from California to Vermont are not about awareness, since they have made sure to exempt numerous products - everything from restaurants to alcohol to food at a deli need not have a GMO label. If the cows that make the milk that go into Stonybrook Farms yogurt eat GMO feed, the yogurt is just as organic. 

As it should be. To science, organic and genetic modification are simply different processes. Nothing about a cow munching on genetically modified food changes the milk.

Cancer vaccines haven't lived up to their promise in clinical trials and the reason, many researchers suspect, is that the immune cells that would help the body destroy the tumor – even those reactions boosted by cancer vaccines – are actively suppressed.

Cancer vaccines are designed to boost the body's natural defenses against cancer. They work by training the immune system to recognize and attack specific tumor peptides, which are a kind of identification tag for tumors. These peptide "tags" help the immune system find and attack cancer cells. There are three types of cells that can "see" and react to these tags: T-helper cells, cytotoxic T cells, and B cells, and researchers thought that all three were trained, or tolerized, to ignore the tags on cancer cells.

A new Neurogrid circuit board can simulate orders of magnitude more neurons and synapses than other brain mimics - on the power it takes to run a tablet computer.

For all their sophistication, computers pale in comparison to the brain. The modest cortex of the mouse, for instance, operates 9,000 times faster than a personal computer simulation of its functions. Not only is the PC slower, it takes 40,000 times more power to run, says Kwabena Boahen, associate professor of bioengineering at Stanford.

It is generally well known that men have an overall shorter life expectancy compared to women. A recent study, led by Uppsala University researchers, shows a correlation between a loss of the Y chromosome in blood cells and both a shorter life span and higher mortality from cancer in other organs.

Men have a shorter average life span than women and both the incidence and mortality in cancer is higher in men than in women. However, the mechanisms and possible risk factors behind this sex-disparity are largely unknown. Alterations in DNA of normal cells accumulate throughout our lives and have been linked to diseases such as cancer and diabetes.