King Alfred burned the cakes, right? Wrong.

A project by University of Wisconsin-Madison researchers has come one step closer to making fusion energy possible.

The research team, headed by electrical and computer engineering Professor David Anderson and research assistant John Canik, recently proved that the Helically Symmetric eXperiment (HSX), an odd-looking magnetic plasma chamber called a stellarator, can overcome a major barrier in plasma research, in which stellarators lose too much energy to reach the high temperatures needed for fusion.


Helically Symmetric Experiment

The first detailed images of an elusive drug target on the outer wall of bacteria may provide scientists with enough new information to aid design of novel antibiotics. The drugs are much needed to treat deadly infections initiated by Staphylococcus aureus and other bacterial pathogens.

The research team, led by Natalie Strynadka, a Howard Hughes Medical Institute (HHMI) international research scholar at the University of British Columbia in Vancouver, Canada, published its findings in the March 9, 2007, issue of the journal Science.


The image shows a substrate based inhibitor in the GT region (blue) of the PBP2 enzyme that blocks bacterial cell wall synthesis.

High performance schools integrate the best in today's design strategies and building technologies. Even better, they make a difference in the way children learn. Research has shown that better buildings produce better student performance, reduce operating costs and increase average daily attendance. They also are more likely to maintain teacher satisfaction and retention and reduce liability exposure.

Deane Evans, FAIA, executive director of the Center for Architecture and Building Science Research at New Jersey Institute of Technology (NJIT), numbers among the nation's top boosters for high-performance schools.

Cuttlefish are well-known masters of disguise who use highly developed camouflage tactics to blend in almost instantaneously with their surroundings. These relatives of octopuses and squid are part of a class of animals called cephalopods and are found in marine habitats worldwide. Cephalopods use camouflage to change their appearance with a speed and diversity unparalleled in the animal kingdom, however there is no documentation to date that they use their diverse camouflage repertoire at night.

A paradigm shift in medical education is needed, one with more emphasis on training future physicians to enhance their empathy skills and to learn to view patients as persons, not just cases, a medical education specialist at Jefferson Medical College says.

"If we want to train physicians with more empathy, then education must shift from emphasizing only the biomedical to also providing a biopsychosocial framework, as well and a more complete picture of patients as persons," says Mohammadreza Hojat, Ph.D., research professor of psychiatry and human behavior at Jefferson Medical College of Thomas Jefferson University in Philadelphia.

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Researchers at the University of Pennsylvania Schools of Medicine and Veterinary Medicine have determined a way to pre-screen cancer patients to see if they are suitable candidates for proteasome inhibitors, a promising class of anti-cancer drugs. They propose to test for p53, a well-known tumor-suppressor protein that is broken down by cellular machinery called proteasomes. This study appears online in the journal Blood, in advance of print publication in June 2007.

In cancer patients whose tumors do not produce p53, proteasome inhibitors might be ineffective. This patient group could be spared unnecessary treatment with possible harmful side effects.

After injury, even adult muscles can heal very well because they have a reserve supply of muscle stem cells, called satellite cells, which they can utilize for repair. Until now, it was unclear how this supply of satellite and muscle progenitor cells, out of which both muscle cells as well as satellite cells develop, keeps itself “fresh”. Developmental biologists Professor Carmen Birchmeier, Dr. Elena Vasyutina, and Diana Lenhard of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now demonstrated that a molecular switch, abbreviated RBP-J, regulates this “fountain of youth”. If the switch is absent, the satellite cells generate muscle cells in an uncontrolled way, resulting in the depletion of the satellite cell reserves.

A group of European researchers has developed a spinal cord model of the salamander and implemented it in a novel amphibious salamander-like robot. The robot changes its speed and gait in response to simple electrical signals, suggesting that the distributed neural system in the spinal cord holds the key to vertebrates’ complex locomotor capabilities.


The EPFL Salamander Robot walks down to the waters of Lake Geneva. Credit: Photograph by A. Badertscher, courtesy Biologically Inspired Robotics Group, EPFL

ver wonder why some women seem to be more ill-tempered than others? University of Pittsburgh researchers have found that behaviors such as anger, hostility and aggression may be genetic, rooted in variations in a serotonin receptor gene. Indrani Halder, Ph.D., of the Cardiovascular Behavioral Medicine Program at the University of Pittsburgh, will present the findings today at the American Psychosomatic Society's Annual Meeting, held in Budapest, Hungary.

Previous studies have associated the hormone serotonin with anger and aggression in both humans and animals and have shown that increased serotonin activity is related to a decrease in angry and aggressive behaviors.