Clinical Research

New: Better Tissue Trauma Repair Than Grafts And Synthetic Material

A breakthrough could speed recovery and limit disfigurement for patients who have suffered large soft tissue trauma, as occurs with serious injury or cancer surgery.   By biomedically engineering a muscle flap that includes a patient's own blood vesse ...

Article - News Staff - Apr 9 2014 - 3:30am

Lab-Grown Vaginas Implanted In 4 Young Patients

A report in The Lancet describes the first instance of human recipients receiving laboratory-grown vaginal organs. The research team describes long-term success in four teenage girls who received the vaginal organs, engineered with their own cells. ...

Article - News Staff - Apr 10 2014 - 11:38pm

5 Patients Get Nose Reconstruction With Cartilage Grown From Their Own Cells

The first ever successful nose reconstruction surgery using cartilage grown in the laboratory has been done by the University of Basel. The details are upcoming in The Lancet. The cartilage cells were extracted from the patient's nasal septum, multip ...

Article - News Staff - Apr 10 2014 - 11:44pm

Fialuridine Redux: New Mouse Model Would Have Predicted Fatal Outcome In Human Clinical Trial

In 1993, five people died in a clinical trial of fialuridine, a nucleoside analogue to treat hepatitis B virus infection. An analysis by the US National Academy of Sciences of all preclinical fialuridine toxicity tests, which included studies in mice, rat ...

Article - News Staff - Apr 15 2014 - 7:00pm

XBiotech Announces Phase I/II Study Results Of Xilonix Anti-tumor Therapy

XBiotech, a company involved in commercializing biological therapies, has published the results from its Phase I/II oncology study conducted at MD Anderson Cancer Center in Houston. The study describes the outcome in 52 advanced cancer patients treated wit ...

Article - News Staff - Apr 20 2014 - 9:11pm

ActiPatch- Randomized, Double Blind, Placebo Controlled Trial Significantly Relieves Knee Pain

Preliminary results of a randomized, double blind, placebo controlled trial on osteoarthritis of the knee using ActiPatch Therapy have been announced. BioElectronics Corporation says the initial interim analysis showed statistically significant results for ...

Article - News Staff - Apr 21 2014 - 10:01am

Stem Cell Clinical Trials: Discrepancies In Data Linked To Success Of Treatment

New research looking at the success of clinical trials of stem cell therapy shows that, when trials appear to be more successful, more discrepancies in trial data are also evident. Discrepancies were defined as two (or more) reported facts that could not ...

Article - News Staff - Apr 28 2014 - 8:44pm

TGF Discovery May Help Treat Brittle Bone Disease

Brittle bone disease is a congenital disorder that results in fragile bones that break easily.   A new study in Nature Medicine showed that excessive activity of an important signaling protein in the matrix of the bone called transforming growth factor be ...

Article - News Staff - May 4 2014 - 3:00pm

Multi-Biomarker Test Identifies Patients Resistant To Pre-Surgical Chemoradiation Therapy

The esophagus carries food and liquid from the mouth to the stomach. There are two main types of esophageal cancer: adenocarcinoma and squamous cell carcinoma. The most common form of the disease in the U.S. is adenocarcinoma and is most prevalent in Cauca ...

Article - News Staff - May 6 2014 - 9:44pm

Synthetic Genomics Signs R&D Agreement To Develop Humanized Pig Organs For Transplantation

Synthetic Genomics announceda multi-year research and development agreement with Lung Biotechnology to develop humanized pig organs using synthetic genomic advances. The collaboration will focus upon developing organs for human patients in need of transpla ...

Article - News Staff - May 6 2014 - 11:08pm