There are things or entities in or on an object that could be present and be proven to exist by experiments and yet one can not see because they are too small to be seen by our naked eyes or some cannot be seen at all. Examples are viruses, bacteria, molecules, ions, atoms, forces, forms of energy, etc.
People of long ago, at around 5th century B.C., a Greek Philosopher named Leucippus thought that water has an ultimate particle that cannot be subdivided. His idea was later expanded by his student, Democritus who named these possible indivisible particles as “atomos”. From there, scientists tried to experiment in order to verify its existence and farther they go into figuring out how ”atomos” looks like.