When you see an article about geckos and their ability to sit upside down, Spider-Man references are sure to follow. And if the topic is that sticky ability in spiders, you will get Spider-Man references and a picture.
Yet even geckos have limits - that's just plain nanophysics.
The fact is, sooner or later the grip is lost, no matter how little force is acting on it. But knowing the limits can have considerable benefits, for instance in the production of graphene - because graphene consists only of one layer of atom, and which must be easily detached from the substrate.