Rats socially isolated during a critical period in adolescence are more vulnerable to addiction to amphetamine and alcohol, according to a new paper. Amphetamine addiction is also harder to extinguish in the socially isolated rats.

These effects persist even after the rats are reintroduced into the community of other rats.

"Basically the animals become more manipulatable," said Hitoshi Morikawa, associate professor of neurobiology in the College of Natural Sciences. "They're more sensitive to reward, and once conditioned the conditioning takes longer to extinguish. We've been able to observe this at both the behavioral and neuronal level."

In a genome-wide analysis of 13 metastatic prostate cancers done on men who died of metastatic prostate cancer and whose tissue samples were collected after a rapid autopsy, scientists found consistent epigenetic signatures across all metastatic tumors in each patient. 

The discovery of stable epigenetic marks that sit on the nuclear DNA of cancer cells and alter gene expression, defies a prevailing belief that the marks vary so much within each individual's widespread cancers that they have little or no value as targets for therapy or as biomarkers for treatment response and predicting disease severity. 

A new image from the Atacama Pathfinder Experiment (APEX) telescope in Chile shows a beautiful view of clouds of cosmic dust nebula NGC 1999 in the region of Orion. While these dense interstellar clouds seem dark and obscured to visible-light observations, APEX’s LABOCA camera can detect the heat glow of the dust and reveal the hiding places where new stars are being formed. But one of these dark clouds is not what it seems.

VTT Technical Research Centre of Finland has developed an automatic ice detection system for cars  that makes use of a new, real-time method of obtaining information on a road's actual slipperiness.  

Obviously, such a system helps drivers avoid personal injuries and damage to vehicles in slippery road conditions. Not only are vehicles are warned in advance of a road's actual slipperiness, if the road becomes slippery, other vehicles arriving in the area will also be warned immediately.
 

Predicting weather events is more mysticism than science and it's only after the fact that predictions are recalibrated to try and hone in on more accuracy.  Hurricane Sandy in the eastern United States was predicted to be a super-storm but by the time it hit New York City was a regular old tropical storm, though one that became a welcome $17 billion federal stimulus plan and a call for action on global warming that did not cause it.

During our zeal to recapture manufacturing like Apple iPhone and solar panel construction during the last four years, something obvious was ignored; the environmental hazards were never going to be acceptable in the USA. The rich people who can afford the latest technology turn a blind eye to non-union wages, slave labor and environmental impact as long as it is happening in th developing world.