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Scientists on the NuMI Off-Axis Electron Neutrino Appearance (NOvA) experiment saw their first evidence of oscillating neutrinos, confirming that the extraordinary detector built for the project not only functions as planned but is also making great progress toward its goal of a major leap in our understanding of these ghostly particles.

Cancer survival in England remains lower than countries with similar healthcare systems, according to a new study. Cancer survival in England has steadily improved but the gap in survival remains.

The research, from the London School of Hygiene&Tropical Medicine, compared survival for colon, breast, lung, ovarian, rectal and stomach cancers in England, Australia, Canada, Denmark, Norway and Sweden between 1995 and 2009, and survival trends in England up to 2012. It included more than 1.9 million cancer patients in England and another 1.9 million cancer patients from the other five countries. The report analyzed data from Australia, Canada, Denmark, Norway and Sweden between 1995 and 2009 and data from England between 1995 and 2012.

Patients with low testosterone levels who have then gone on to have testosterone replacement therapy (TRT) could be at lower risk of cardiovascular events such as heart attack or stroke, according to research published today (Thursday) in the European Heart Journal.

In the study, researchers from Kansas City VA Medical Centre in Kansas City, USA, examined the effect of TRT on cardiovascular outcomes by comparing incidences of heart attack, stroke, and all-cause mortality among different sub-populations of treated and untreated patients. The study used the largest cohort of patients and the longest follow-up for TRT to date.

The non-medical use of prescription opioids (POs) has become an area of increasing public health concern in the United States and rates of use are particularly high among young adults. In the past decade, an emerging "epidemic" of non-medical PO use has been reported.

Among young adults, self-reported use is 11% and overdose deaths involving POs now exceed deaths involving heroin and cocaine combined. Sexual violence is also a serious problem in the United States receiving increased national attention, and the relationship between substance use and sexual violence is well supported in the literature.

Researchers have identified a protein produced by white blood cells that puts the brakes on muscle repair after injury.

By removing the protein CD163 from mice, scientists at Emory University School of Medicine could boost muscle repair and recovery of blood flow after ischemic injury (damage caused by restriction of blood flow).

The findings point to a target for potential treatments aimed at enhancing muscle regeneration. Muscle breakdown occurs in response to injury or inactivity -- during immobilization in a cast, for example -- and in several diseases such as diabetes and cancer.

The results are scheduled for publication online by Nature Communications on August 5.

Even before President Obama announced the Environmental Protection Agency’s (EPA) Clean Power Plan on August 3 to regulate carbon emissions from power plants, there were a number of legal challenges to block the law at its proposal stage – none of them successful. Earlier this year, the DC Circuit court told opponents, which included a coal company joined by twelve states, that their arguments were premature.

Now that the rules are final, the new court challenges will come fast and heavy. The legal arguments against the plan will be focused on two issues.