Ten genetic variants associated with type 2 diabetes, a disease which impacts more than 170 million people worldwide, have been identified or confirmed by a U.S.-Finnish team led by scientists at the University of Michigan School of Public Health.

The discoveries could lead to the development of new drugs for diabetes, permit more effective targeting of drug and behavioral therapies, and help scientists and physicians better predict who will develop diabetes, said Michael Boehnke, the Richard G. Cornell Collegiate Professor of Biostatistics at the U-M School of Public Health.

Engineers at Washington University in St.

Scientists at The University of Nottingham have been awarded over £366,000 to help unravel the mystery of a stomach bug which causes gastric ulcers and cancer. Their research could lead to the development of a vaccine for those most at risk.

Studies of the enzyme CTP synthetase in the parasite Trypanosoma brucei have brought researchers at Umeå University in Sweden closer to a cure for African sleeping sickness. Their findings are now being published in the April issue of The Journal of Biological Chemistry.

Since the parasite constantly changes its surface, it can avoid the immune defense of humans and invade the central nervous system, which leads to personality disturbances, sleep disruptions, and ultimately death. For patients affected by a severe T brucei infection in the central nervous system, there are no medicines that can treat both subspecies without incurring extremely serious side effects.

Nanotechnology is the ability to measure, see, manipulate and manufacture things usually between 1 and 100 nanometers. A nanometer is one billionth of a meter; a human hair is roughly 100,000 nanometers wide. More than $30 billion in products incorporating nanotechnology were sold globally in 2005. By 2014, Lux Research estimates this figure will grow to $2.6 trillion.

As products made with nanometer-scale materials and devices spread to more industries and markets, there is a growing opportunity and responsibility to leverage nanotechnology to reduce pollution, conserve resources and, ultimately, build a "clean" economy, advises a new report from the Project on Emerging Nanotechnologies.

An electrical circuit that should carry enough power to produce the long-sought goal of controlled high-yield nuclear fusion and, equally important, do it every 10 seconds, has undergone extensive preliminary experiments and computer simulations at Sandia National Laboratories' Z machine facility.

Z, when it fires, is already the largest producer of X-rays on Earth and has been used to produce fusion neutrons. But rapid bursts are necessary for future generating plants to produce electrical power from sea water.