Pharmacology

HUMIRA Approved In Europe For Severe Active Pediatric Crohn's Disease

The European Commission has approved  Abbott's HUMIRA® (adalimumab) for the treatment of pediatric patients aged 6 to 17 years with severe active Crohn's disease (CD) who failed, are intolerant to, or have contraindications to conventional thera ...

Article - News Staff - Nov 27 2012 - 9:00am

Chronic Myeloid Leukemia Mutation Thwarted By Ponatinib

A previously invincible mutation in chronic myeloid leukemia (CML) has been thwarted by an investigational drug in a phase I clinical trial. 12 patients in a trial with chronic phase CML and the T315I mutation had a complete hematologic response (absence ...

Article - News Staff - Dec 2 2012 - 6:49pm

Merck Serono Donates 100 Millionth Tablet For Schistosomiasis Treatment

Merck Serono, a division of Merck, has donated its 100 millionth praziquantel tablet to the World Health Organization (WHO). ...

Article - News Staff - Nov 29 2012 - 12:17pm

Psychotropic Medication Prevalence In US Adolescents With Mental Disorders

A survey published in Archives of Pediatrics&Adolescent Medicine  finds that 14.2 percent of teenage children with any mental disorder have been treated with a psychotropic medication in the last 12 months, which researchers suggest challenges concern ...

Article - News Staff - Dec 4 2012 - 2:30pm

Largest Safety Trial Of Erwinaze To Date For Acute Lymphoblastic Leukemia

...

Article - News Staff - Dec 10 2012 - 9:53pm

Anabolic Androgenic Steroid Use Impacts Visuospatial Memory

The ability to accurately recall the shapes and spatial relationships of objects has been shown to be reduced by long-term use of anabolic-androgenic steroids (AAS), according to a recent paper.  ...

Article - News Staff - Dec 17 2012 - 4:31am

Phase I Trial For Pharmacokinetics Of KU-046 In Alzheimer's Disease

Kareus Therapeutics SA has announced the start of a Phase I clinical study following the Investigational New Drug (IND) approval from the US Food and Drug Administration for the development of KU-046, a first-in-class disease modifying new chemical entity ...

Article - News Staff - Jan 5 2013 - 9:30am

Phase 3 Registration Trial In Mildly Infected Diabetic Foot Ulcers With Locilex

...

Article - News Staff - Jan 4 2013 - 9:30am

FDA Approves Rebif Rebidose Interferon Beta-1a For Multiple Sclerosis

Merck Serono, a division of Germany's Merck, announced that the U.S. Food and Drug Administration (FDA) approved Rebif(R) Rebidose(R) (interferon beta-1a), a single-use auto-injector for the self-administration of Rebif, a disease-modifying drug used ...

Article - News Staff - Jan 3 2013 - 11:01am

Delivering Bifidobacterium

Some years ago, I was a bit mystified as to the distinction between prebiotics and probiotics.  These days, one can easily look them up on Wikipedia, and find that prebiotics are meant to encourage the growth of ‘good’ bacteria in the gut, while probiotic ...

Article - Robert H Olley - Jan 10 2013 - 5:05am