Scientists have discovered epigenetic changes (i.e. chemical changes to a gene that do not alter the DNA sequence) in individuals with schizophrenia and bipolar disorder. This is the first epigenome-wide investigation in psychiatric research, and this groundbreaking data may be a significant step on the journey to fully understanding major psychosis.

Dr. Arturas Petronis, senior scientist in the Krembil Family Epigenetic Laboratory at the Centre for Addiction and Mental Health (CAMH), and his team studied 12,000 locations on the genome using an epigenomic profiling technology developed at CAMH. Approximately one in every two hundred of these genes showed an epigenetic difference in the brains of psychiatric patients.

Significantly, these changes were noted on genes involved in neurotransmission (the exchange of chemical messages within the brain), brain development, and other processes linked to disease origins.

Ant colonies are always used as the model for working together rather than for individual gain but that isn't so, say researchers from the University of Leeds and the University of Copenhagen. Dr. Bill Hughes and Professor Jacobus Boomsma say they have found evidence that, far from being a model of social cooperation, the ant world is riddled with cheating and corruption – and it goes all the way to the top.

Certain ants, they say, are able to cheat the system, ensuring their offspring become reproductive queens rather than sterile workers.

It's Gattaca, except with ants.

In the largest and longest study to date of weight loss maintenance strategies, researchers at Duke University Medical Center found that personal contact – and, to a lesser extent, a computer-based support system – were helpful in keeping weight off.

“The results of this study send a strong signal to those who seem to believe that obesity is such an intractable problem that nothing can be done about it,” says Dr. Laura Svetkey, professor of medicine at Duke and the lead author of the study. “Our research shows that is not true. A large majority of the participants in the Weight Loss Management study lost weight and kept weight off for two and one-half years.”

Rather than improving motorist safety, red-light cameras significantly increase crashes and are a ticket to higher auto insurance premiums, researchers at the University of South Florida College of Public Health conclude.

“The rigorous studies clearly show red-light cameras don’t work,” said lead author Barbara Langland-Orban, professor and chair of health policy and management at the USF College of Public Health. “Instead, they increase crashes and injuries as drivers attempt to abruptly stop at camera intersections. If used in Florida, cameras could potentially create even worse outcomes due to the state’s high percent of elderly who are more likely to be injured or killed when a crash occurs.”

Science has developed sophisticated models of the atmosphere and instruments can help make detailed weather forecasts but to truly understand global climate change, scientists need more than just a one-day forecast or a seven-day guess. They need a deeper understanding of the complex and interrelated forces that shape climate.

They need applied mathematics, says Brad Marston, professor of physics at Brown University. He is working on sets of equations that he says can be used to more accurately explain climate patterns.

“Climate is a statement about the statistics of weather, not the day-to-day or minute-by-minute fluctuations,” Marston said. “That’s really the driving concept. We know we can’t predict the weather more than a couple of weeks out.

Snakes don't eat fugu, the seafood delicacy prepared from blowfish meat and famed for its poisonous potential. However, should a common garter snake wander into a sushi restaurant, it could fearlessly order a fugu dinner.

The snakes have evolved resistance to the blowfish poison, tetrodotoxin (TTX), by preying on rough-skinned newts, which also secrete the toxin. Some newts are so poisonous that they harbor enough TTX to kill a roomful of adult humans.

Why would a small animal produce such an excessive amount of poison" The answer lies in the evolutionary back-and-forth between newts and garter snakes.

Researchers at the National Institute of Standards and Technology (NIST) and the University of Maryland have developed a new optical method that can detect individual neutrons and record them over a range of intensities at least a hundred times greater than existing detectors.

The new detector, described at the March Meeting of the American Physical Society by Charles Clark, a Fellow of the Joint Quantum Institute of NIST and the University of Maryland, promises to improve existing neutron measurements and enable tests of new phenomena beyond the Standard Model, the basic framework of particle physics.

A researcher at the National University in San Diego has taken a mathematical approach to a biological problem - how to design a portable DNA detector. Samuel Afuwape, Applied Engineering professor, describes a mathematical simulation to show how a new type of nanoscale transistor might be coupled to a DNA sensor system to produce a characteristic signal for specific DNA fragments in a sample.

Afuwape explains that a portable DNA sequencer could make life easier for environmental scientists testing contaminated sites. Clinicians and medical researchers too could use it to diagnose genetic disorders and study problems in genetics. Such a sensor might also be used to spot the weapons of the bioterrorist or in criminal forensic investigations.

The growth in China's carbon dioxide (CO2) emissions is far outpacing previous estimates, making the goal of stabilizing atmospheric greenhouse gases much more difficult, according to a new analysis by economists at the University of California, Berkeley, and UC San Diego.

Previous estimates, including those used by the Intergovernmental Panel on Climate Change, say the region that includes China will see a 2.5 to 5 percent annual increase in CO2 emissions, the largest contributor to atmospheric greenhouse gases, between 2004 and 2010. The new UC analysis puts that annual growth rate for China to at least 11 percent for the same time period.

An international group of researchers has found evidence for the earliest transport use of the donkey and the early phases of donkey domestication, suggesting the process of domestication may have been slower and less linear than previously thought.

Based on a study of 10 donkey skeletons from three graves dedicated to donkeys in the funerary complex of one of the first Pharaoh's at Abydos, Egypt, the team, led by Fiona Marshall, Ph.D., professor of Anthropology at Washington University in St. Louis, and Stine Rossel of the University of Copenhagen, found that donkeys around 5,000 years ago were in an early phase of domestication. They looked like wild animals but displayed joint wear that showed that they were used as domestic animals.