Researchers at Children’s Hospital Boston have developed a new “nanobiotechnology” that enables magnetic control of events at the cellular level. They describe the technology, which could lead to finely-tuned but noninvasive treatments for disease, in the January issue of Nature Nanotechnology.
Don Ingber, MD, PhD, and Robert Mannix, PhD, of Children’s program in Vascular Biology, in collaboration with Mara Prentiss, PhD, a physicist at Harvard University, devised a way to get tiny beads – 30 nanometers (billionths of a meter) in diameter – to bind to receptor molecules on the cell surface.
When exposed to a magnetic field, the beads themselves become magnets, and pull together through magnetic attraction.