Metabolites - substances that are created during metabolism -- can provide a wealth of information about individual health, disease, diet, and life-style. Now, they can tell us even more. Okinawa Institute of Science and Technology Graduate University (OIST) researchers and collaborators at Kyoto University have recently discovered metabolites that are specifically related to aging and shed light on how the human body ages. The team, led by OIST's Professor Yanagida, published their results in PNAS.

A large, multi-center study led by the UC Davis School of Medicine for the first time has shown that people as young as their 40s have stiffening of the arteries that is associated with subtle structural damage to the brain that is implicated in cognitive decline and Alzheimer's disease later in life.

A collaboration of UC Davis, the Framingham Heart Study and Boston University, among others, the study found that, among young healthy adults, higher aortic "stiffness" was associated with reduced white matter volume and decreased integrity of the gray matter, and in ages much younger than previously described.

Like most annuals, lettuce plants live out their lives in quiet, three-act dramas that follow the seasons. Seed dormancy gives way to germination; the young plant emerges and grows; and finally in the climax of flowering, a new generation of seeds is produced. It's remarkably predictable, but the genetics that coordinates these changes with environmental cues has not been well understood.

EAST LANSING, Mich. -- Sexual harassment remains a pervasive problem in India despite tougher laws enacted more than three years ago after a woman was gang raped on a bus and later died of her injuries, indicates new research by a Michigan State University criminologist.

About 40 percent of women surveyed in Delhi said they have been sexually harassed in a public place such as a bus or park in the past year, with most of the crimes occurring in the daytime. Further, 33 percent of women have stopped going out in public and 17 percent have quit their jobs rather than face harassment, or worse, in public places.

Most non-Africans possess at least a little bit Neanderthal DNA. But a new map of archaic ancestry--published March 28 in Current Biology--suggests that many bloodlines around the world, particularly of South Asian descent, may actually be a bit more Denisovan, a mysterious population of hominids that lived around the same time as the Neanderthals. The analysis also proposes that modern humans interbred with Denisovans about 100 generations after their trysts with Neanderthals.

CORVALLIS, Ore. - A new analysis of the prehistoric origin of malaria suggests that it evolved in insects at least 100 million years ago, and the first vertebrate hosts of this disease were probably reptiles, which at that time would have included the dinosaurs.

Malaria, a scourge on human society that still kills more than 400,000 people a year, is often thought to be of more modern origin - ranging from 15,000 to 8 million years old, caused primarily by one genus of protozoa, Plasmodium, and spread by anopheline mosquitoes.

Vanishing Arctic sea ice, dogged weather systems over Greenland, far-flung surface ice melting on the massive island - these trends and global sea-level rise are linked by climate change, according to a new paper.

During Greenland summers, melting Arctic sea ice favors stronger and more frequent "blocking-high" pressure systems, which spin clockwise, stay largely in place and can block cold, dry Canadian air from reaching the island. The highs tend to enhance the flow of warm, moist air over Greenland, contributing to increased extreme heat events and surface ice melting, according to the computer models and field measurements 
in the Journal of Climate.

By Gabriel Popkin, Inside Science -- When leaders of the Laser Interferometer Gravitational-wave Observatory, or LIGO, announced in February the first-ever direct detection of a gravitational wave, astrophysicists Scott Ransom from the National Radio Astronomy Observatory and Andrea Lommen at Franklin and Marshall University in Lancaster, Pennsylvania, had mixed feelings.

“What if you could cure all your health problems and lose 10 pounds in just 7 days? That’s an amazing claim, hard to believe for sure, but I have seen this miracle so many times in my practice that even I am starting to believe it!”

Straight away, the words of Dr. Mark Hyman, sometime physician to Bill Clinton, talk-show regular and bestselling author, set off alarm bells. He’s promoting an “anti-inflammatory”, “detox” diet.

Scholars have identified a single, universal facial expression that is interpreted across many cultures as the embodiment of negative emotion. That includes native speakers of English, Spanish, Mandarin Chinese and American Sign Language (ASL).

We've all seen it. It consists of a furrowed brow, pressed lips and raised chin, and because we make it when we convey negative sentiments, such as "I do not agree." It is called the "not" face.