This isn't news anymore (see here, and here), but Bruce Alberts, Editor-in-Chief of Science has weighed in on the out-of-whack system of incentives in the biomedical sciences:

Our neurological structures are made mainly for survival; curiosity (a main tool for living) and its satisfaction are deeply inserted, by evolutionary genetics, into our central nervous system because of the need to find solutions to make sure survival. You can react in a rush moment like you never thought before, in order of the life maintenance, and until later think about the efficacy of your instinctive reaction. So our brain works to find solutions to the daily challenges of life, like most of the living species do so.