Writing in the latest issue of JAMA, Alec B. O'Connor, associate professor at the University of Rochester Medical Center, says the federal guidelines governing the approval of potential new drugs should be much more stringent. The FDA, according to the commentary, should require studies comparing the effectiveness and safety of a new drug to an established first-line drug when considering a drug for approval.

Currently the agency does not require such studies, known as "active comparator trials," though some large studies of new drugs do include them. In many cases, to gain approval, the main criterion besides safety is that a new drug must be shown to be more effective than placebo.
A team of astronomers writing in Astrophysical Journal Letters has shown that the two stars in the binary HM Cancri revolve around each other in a mere 5.4 minutes, making HM Cancri the binary star with by far the shortest known orbital period. It is also the smallest known binary; The system is no larger than 8 times the diameter of the Earth.

The team was able to prove the short binary period of the system by detecting the velocity variations in the spectral lines in the light of HM Cancri. These velocity variations are induced by the Doppler effect, caused by the orbital motion of the two stars revolving around each other. The Doppler effect causes the lines to periodically shift from blue to red and back.
Researchers at Yale School of Medicine have discovered that exposure during pregnancy to Bisphenol A (BPA), a common component of plastics, causes permanent abnormalities in the uterus of offspring, including alteration in their DNA. The findings were reported the Journal of the Federation of American Societies for Experimental Biology (FASEB J.).

The authors say the study is the first to show that BPA exposure permanently affects sensitivity to estrogen.
Scientists from the U.S. department of Agriculture have discovered how The Aedes aegypti mosquito detects the chemical structure of a compound called octenol as one way to find a mammalian host for a blood meal.

Scientists have long known that mosquitoes can detect octenol, but this most recent finding, published in PLoS One, explains in greater detail how Ae. aegypti--and possibly other mosquito species--detect the compound.
Using data from two recent national surveys, University of Toronto sociologist Scott Schieman has found that most Americans believe God is concerned with their well-being and is directly involved in their personal affairs.

The research, he says, uncovered  the ways these beliefs about divine intervention differ across education and income levels. The results are published in Sociology of Religion.
Traditionally, scientists believed that nicotine inhaled in a puff of cigarette smoke took a mere seven seconds to be taken up by the brain, but new evidence indicates that nicotine takes much longer to reach peak levels in the brains of cigarette smokers, according to a new study in PNAS.

Using PET imaging, Duke investigators found for the first time that cigarette smokers actually experience a steady rise of brain nicotine levels during the course of smoking a whole cigarette.
Natural Killer (NK) cells ensnare dangerous cells, such as tumour cells and those infected with bacteria and viruses that are on the run with a bungee-like nanotube, according to research published this week in PNAS. The study shows that NK cells use this bungee to destroy cells that could otherwise escape them.

Researchers are keen to understand how NK cells work because they help the body to fight infection and stop tumours from growing. It is thought that it may ultimately be possible to design drugs that harness the cells' ability to fight disease.
In the past week or two, there have been several news stories and blogs (including here on SB) written in regards to a paper that came out this month titled, "Why Liberals and Atheists Are More Intelligent". It would be easy for the untrained eye to read such a headline and think, "Gee.... this was published in a peer reviewed journal, so this must really be something..." However, if you read through the paper in detail, and look at the longitudinal data methods used for the analysis, one begins to question the validity of such broad assumptions.
The jokes just write themselves, really. But poor sanitation is no laughing matter, especially if you're one of the 2.6 billion people on Earth without access to a toilet. And for pennies on the dollar, a Swedish entrepreneur is hoping to help that 40% of the world's population in more ways than one.
Imagine a child, standing in a school cafeteria. We'll assume that this child has reached or surpassed the age of reason (7 years old, for non-Catholics out there), meaning they can understand their choices and therefore can make the wrong choice along with the right one.

In front of this lovely child is a vending machine filled with tempting soda1 and sports drinks and other such calorie-laden, battery-acid-by-another-name, neatly packaged consumables.