A biomarker found in the blood of alcohol users is significantly higher in binge drinkers than in those who consume alcohol moderately, according to a study by researchers at the University of Illinois at Chicago. The biomarker, called phosphatidylethanol (PEth), could be used to screen young adults for harmful or heavy drinking such as binge drinking.

Having performed extensive research on alcohol and its effects on health throughout her career, Mariann Piano, professor and head of the department of biobehavioral health science in the UIC College of Nursing, knew PEth is a biomarker associated with alcohol consumption, but it had never been measured in young adults.

A new study by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP), the National Cancer Institute, and the Chulabhorn Research Institute has found that blocking the activity of a key immune receptor, the lymphotoxin-beta receptor (LTβR), reduces the progression of liver cancer. The results, published today in the online edition of Gut, could provide new treatment strategies for the disease, which is the third leading cause of cancer-related deaths worldwide.

Looking at measurements of the vertebrae - the series of small bones that make up the spinal column - in newborn children, investigators at Children's Hospital Los Angeles found that differences between the sexes are present at birth. Results of the study, now online in advance of publication in the August issue of the Journal of Pediatrics, suggest that this difference is evolutionary, allowing the female spine to adapt to the fetal load during pregnancy.

Using magnetic resonance imagining (MRI), the researchers found that vertebral cross-sectional dimensions, a key structural determinant of the vertebra's strength, were 10.6 percent smaller on average in newborn females than in males.

A new University of Michigan study finds that teens using marijuana for medical reasons are 10 times more likely to say they are hooked on marijuana than youth who get marijuana illegally.

The study is the first to report on a nationally representative sample of 4,394 high school seniors and their legal or illegal medical marijuana use as it relates to other drug use. In the study, 48 teens had medical marijuana cards, but 266 teens used medical marijuana without a card.

Scientific research sometimes requires the use of animals. It’s a fact. And as long as that is the case, we need to do everything in our power to minimize the distress for laboratory animals.

This is not just for the sake of the animals, but also for the sake of science itself. We know that the quality of life of an animal can actually affect its physiology and, thereby, the research data.

But unfortunately, the standards of animal care vary greatly across countries and even across research institutes. The time has come to overhaul this system and replace it with globally enforced rules.

“I saw a werewolf with a Chinese menu in his hand,

Walkin' through the streets of Soho in the rain,

He was lookin' for the place called Lee Ho Fooks,

Gonna get a big dish of beef chow mein.”

Aaahoo! …."

Warren Zevon, 1978

What if I told you that half of the studies published in scientific journals today – the ones upon which news coverage of medical advances is often based – won’t hold up under scrutiny? You might say I had gone mad. No one would ever tolerate that kind of waste in a field as important – and expensive, to the tune of roughly US$30 billion in federal spending per year – as biomedical research, right? After all, this is the crucial work that hunts for explanations for diseases so they can better be treated or even cured.

Researchers studying wild banded mongooses in Uganda have discovered that these small mammals have either cooperative or selfish personalities which last for their entire lifetime.

The researchers investigated the selfish behavior of mongoose mate-guarding - where dominant males guard particular females - and the cooperative behavior of 'babysitting' and 'escorting' the young.

They found that cooperative mongooses that helped out with offspring care did so consistently over their whole lifetime but those that put in little effort never increased their workload.

Similar consistent behavior was found in mongooses that selfishly guarded mates for their entire life.

Antonio Aledo, Professor of Sociology at the University of Alicante, warns that "because of real estate speculation and the management of public budgets based on income from the real estate business, seismic risk has been forgotten."

As an example, he used the town of Torrevieja, where one of the biggest earthquakes in the province of Alicante took place in 1829 with more than 389 dead and 209 wounded. And things would not be much better now.

Scientists have reconstructed part of the male chromosome in polar bears. They were able to assign 1.9 million base pairs specifically to the polar bear Y chromosome and show that more than 100,000 years ago, the male polar bear lineages split and developed in two separate genetic groups.

The polar bear is the world’s largest land-dwelling predator and is hard to miss. Nevertheless, it is difficult to study the evolution this arctic resident: Polar bears live and die on the frozen sea, and their remains are seldom found.

“In order to gain insights into the evolutionary development of Ursus maritimus, we use genetics instead of fossils,” explains Prof. Axel Janke of the Senckenberg Research Institute for Biodiversity and Climate in Frankfurt.