A new small molecule may help people with benzodiazepine-resistant epilepsy. Epilepsy affects an estimated 3.4 million people in the U.S. and millions more worldwide and drugs work for most, but for the rest, Uncontrolled epilepsy and resulting frequent and prolonged seizures lasting five minutes or more that can cause brain cell damage and even death.

Epilepsy occurs when the intricate, delicate balance of signaling by neurons in the brain malfunctions, causing neurons to fire too much and trigger seizures. Benzodiazepines slow down the messages traveling between neurons. Yet up to 30 percent develop drug-resistance after a period of time.

An analysis of the 1.5 million-year-old cranium DAN5/P1, found at the Gona site in Ethiopia, has cranial cranial morphology which indicates that it belongs to the species Homo erectus but near the earliest African stage, where it is sometimes identified using the name H. ergaster.

The fossil is very small for these hominin groups and suggest that its cerebral morphology does not present any traits distinctive to the human genus: its proportions are similar to those of australopiths or species whose evolutionary position, and whether they are from our own lineage, remains to be determined, as is the case with H. habilis.

DART, NASA’s successful double asteroid redirection test in September 2022, had an impact greater than engineers expected - and that means the ability to more accurately move asteroids on a collision course will be greater in the future.

An analysis of the results found the momentum was significantly enhanced by the recoil created from streams of particles produced by the impact.

If you believe your electric car is not using the 80 percent of electricity generated by conventional fuels, you may also believe the high cost is worth it to save the environment. But there is no running from the environmental problems created by the cars themselves. 

There can be no sustainable value chain when we haven't had new batteries in 30 years. Unfortunately, as long as mandates and subsidies are in effect, there is no incentive to create better technology, which means the only hope is to reuse old, inefficient batteries in order to mitigate the high social and environmental toll electric cars extract now.

To adult audiences in 1977, "Star Wars" was the most realistic special effects they had ever witnessed while to younger people of today, the defects are obvious. Some of that is due to better technology, a cheap TV has better clarity and resolution that an IMAX screen a generation ago, but some of it is that they are trained to see better.

Imidazole dipeptides have been been linked to beneficial effects such as relieving fatigue and, with far less credibility, preventing dementia, and a new study has found that 2-oxo-imidazole-containing dipeptides (2-oxo-IDPs), which have one more oxygen atom than normal imidazole dipeptides, are the most common variety of imidazole dipeptides derivatives in the body.